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Page 1
Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia.
Smeenk L, Ottema S, Mulet-Lazaro R, Ebert A, Havermans M, Varea AA, Fellner M, Pastoors D, van Herk S, Erpelinck-Verschueren C, Grob T, Hoogenboezem RM, Kavelaars FG, Matson DR, Bresnick EH, Bindels EM, Kentsis A, Zuber J, Delwel R. Smeenk L, et al. Among authors: kavelaars fg. Cancer Discov. 2021 Nov;11(11):2868-2883. doi: 10.1158/2159-8290.CD-20-1793. Epub 2021 May 12. Cancer Discov. 2021. PMID: 33980539 Free PMC article.
Acquired mutations in ASXL1 in acute myeloid leukemia: prevalence and prognostic value.
Pratcorona M, Abbas S, Sanders MA, Koenders JE, Kavelaars FG, Erpelinck-Verschueren CA, Zeilemakers A, Löwenberg B, Valk PJ. Pratcorona M, et al. Among authors: kavelaars fg. Haematologica. 2012 Mar;97(3):388-92. doi: 10.3324/haematol.2011.051532. Epub 2011 Nov 4. Haematologica. 2012. PMID: 22058207 Free PMC article.
Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations.
Abbas S, Sanders MA, Zeilemaker A, Geertsma-Kleinekoort WM, Koenders JE, Kavelaars FG, Abbas ZG, Mahamoud S, Chu IW, Hoogenboezem R, Peeters JK, van Drunen E, van Galen J, Beverloo HB, Löwenberg B, Valk PJ. Abbas S, et al. Among authors: kavelaars fg. Haematologica. 2014 May;99(5):848-57. doi: 10.3324/haematol.2013.095604. Epub 2014 Jan 17. Haematologica. 2014. PMID: 24441149 Free PMC article.
MicroRNA-155 induces AML in combination with the loss of C/EBPA in mice.
Alemdehy MF, de Looper HW, Kavelaars FG, Sanders MA, Hoogenboezem R, Löwenberg B, Valk PJ, Touw IP, Erkeland SJ. Alemdehy MF, et al. Among authors: kavelaars fg. Leukemia. 2016 Nov;30(11):2238-2241. doi: 10.1038/leu.2016.171. Epub 2016 Jun 4. Leukemia. 2016. PMID: 27363282 No abstract available.
Lack of splice factor and cohesin complex mutations in pediatric myelodysplastic syndrome.
Obenauer JC, Kavelaars FG, Sanders MA, Hoogenboezem RM, de Vries AC, van Strien PM, de Haas V, Locatelli F, Hasle H, Valk PJ, Touw IP, van den Heuvel-Eibrink MM. Obenauer JC, et al. Among authors: kavelaars fg. Haematologica. 2016 Dec;101(12):e479-e481. doi: 10.3324/haematol.2016.151753. Epub 2016 Sep 1. Haematologica. 2016. PMID: 27587384 Free PMC article. No abstract available.
Recurrently affected genes in juvenile myelomonocytic leukaemia.
Obenauer JC, Kavelaars FG, Sanders MA, de Vries ACH, de Haas V, Beverloo HB, De Moerloose B, Lammens T, Dworzak M, Hoogenboezem RM, Valk PJM, Touw IP, van den Heuvel-Eibrink MM. Obenauer JC, et al. Among authors: kavelaars fg. Br J Haematol. 2018 Jul;182(1):135-138. doi: 10.1111/bjh.14737. Epub 2017 May 9. Br J Haematol. 2018. PMID: 28485469 Free article. No abstract available.
Molecular Minimal Residual Disease in Acute Myeloid Leukemia.
Jongen-Lavrencic M, Grob T, Hanekamp D, Kavelaars FG, Al Hinai A, Zeilemaker A, Erpelinck-Verschueren CAJ, Gradowska PL, Meijer R, Cloos J, Biemond BJ, Graux C, van Marwijk Kooy M, Manz MG, Pabst T, Passweg JR, Havelange V, Ossenkoppele GJ, Sanders MA, Schuurhuis GJ, Löwenberg B, Valk PJM. Jongen-Lavrencic M, et al. Among authors: kavelaars fg. N Engl J Med. 2018 Mar 29;378(13):1189-1199. doi: 10.1056/NEJMoa1716863. N Engl J Med. 2018. PMID: 29601269 Free article.
MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML.
Sanders MA, Chew E, Flensburg C, Zeilemaker A, Miller SE, Al Hinai AS, Bajel A, Luiken B, Rijken M, Mclennan T, Hoogenboezem RM, Kavelaars FG, Fröhling S, Blewitt ME, Bindels EM, Alexander WS, Löwenberg B, Roberts AW, Valk PJM, Majewski IJ. Sanders MA, et al. Among authors: kavelaars fg. Blood. 2018 Oct 4;132(14):1526-1534. doi: 10.1182/blood-2018-05-852566. Epub 2018 Jul 26. Blood. 2018. PMID: 30049810 Free PMC article.
29 results