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Copper biology.
Tsang T, Davis CI, Brady DC. Tsang T, et al. Among authors: brady dc. Curr Biol. 2021 May 10;31(9):R421-R427. doi: 10.1016/j.cub.2021.03.054. Curr Biol. 2021. PMID: 33974864 Free article. Review.
Combined Menin and EGFR Inhibitors Synergize to Suppress Colorectal Cancer via EGFR-Independent and Calcium-Mediated Repression of SKP2 Transcription.
Katona BW, Glynn RA, Paulosky KE, Feng Z, Davis CI, Ma J, Berry CT, Szigety KM, Matkar S, Liu Y, Wang H, Wu Y, He X, Freedman BD, Brady DC, Hua X. Katona BW, et al. Among authors: brady dc. Cancer Res. 2019 May 1;79(9):2195-2207. doi: 10.1158/0008-5472.CAN-18-2133. Epub 2019 Mar 15. Cancer Res. 2019. PMID: 30877106 Free PMC article.
The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation.
Grasso M, Bond GJ, Kim YJ, Boyd S, Matson Dzebo M, Valenzuela S, Tsang T, Schibrowsky NA, Alwan KB, Blackburn NJ, Burslem GM, Wittung-Stafshede P, Winkler DD, Marmorstein R, Brady DC. Grasso M, et al. Among authors: brady dc. J Biol Chem. 2021 Dec;297(6):101314. doi: 10.1016/j.jbc.2021.101314. Epub 2021 Oct 27. J Biol Chem. 2021. PMID: 34715128 Free PMC article.
Connecting copper and cancer: from transition metal signalling to metalloplasia.
Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, Ralle M, Schilsky ML, Tonks NK, Vahdat LT, Van Aelst L, Xi D, Yuan P, Brady DC, Chang CJ. Ge EJ, et al. Among authors: brady dc. Nat Rev Cancer. 2022 Feb;22(2):102-113. doi: 10.1038/s41568-021-00417-2. Epub 2021 Nov 11. Nat Rev Cancer. 2022. PMID: 34764459 Free PMC article. Review.
Loss of p19Arf promotes fibroblast survival during leucine deprivation.
Roby KC, Lieberman A, Kim BJ, Rodríguez NZ, Posimo JM, Tsang T, Verginadis II, Puré E, Brady DC, Koumenis C, Ryeom S. Roby KC, et al. Among authors: brady dc. Biol Open. 2022 Feb 15;11(2):bio058728. doi: 10.1242/bio.058728. Epub 2022 Feb 17. Biol Open. 2022. PMID: 34994382 Free PMC article.
54 results