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Gold(I) Phosphine Derivatives with Improved Selectivity as Topically Active Drug Leads to Overcome 5-Nitroheterocyclic Drug Resistance in Trichomonas vaginalis.
Miyamoto Y, Aggarwal S, Celaje JJA, Ihara S, Ang J, Eremin DB, Land KM, Wrischnik LA, Zhang L, Fokin VV, Eckmann L. Miyamoto Y, et al. Among authors: ihara s. J Med Chem. 2021 May 27;64(10):6608-6620. doi: 10.1021/acs.jmedchem.0c01926. Epub 2021 May 11. J Med Chem. 2021. PMID: 33974434 Free PMC article.
Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis.
Lauwaet T, Miyamoto Y, Ihara S, Le C, Kalisiak J, Korthals KA, Ghassemian M, Smith DK, Sharpless KB, Fokin VV, Eckmann L. Lauwaet T, et al. Among authors: ihara s. PLoS Negl Trop Dis. 2020 Apr 17;14(4):e0008224. doi: 10.1371/journal.pntd.0008224. eCollection 2020 Apr. PLoS Negl Trop Dis. 2020. PMID: 32302296 Free PMC article.
Conserved metabolic enzymes as vaccine antigens for giardiasis.
Ihara S, Miyamoto Y, Le CHY, Tran VN, Hanson EM, Fischer M, Hanevik K, Eckmann L. Ihara S, et al. PLoS Negl Trop Dis. 2022 Apr 25;16(4):e0010323. doi: 10.1371/journal.pntd.0010323. eCollection 2022 Apr. PLoS Negl Trop Dis. 2022. PMID: 35468132 Free PMC article.
c-Jun N-terminal kinase in pancreatic tumor stroma augments tumor development in mice.
Sato T, Shibata W, Hikiba Y, Kaneta Y, Suzuki N, Ihara S, Ishii Y, Sue S, Kameta E, Sugimori M, Yamada H, Kaneko H, Sasaki T, Ishii T, Tamura T, Kondo M, Maeda S. Sato T, et al. Among authors: ihara s. Cancer Sci. 2017 Nov;108(11):2156-2165. doi: 10.1111/cas.13382. Epub 2017 Sep 18. Cancer Sci. 2017. PMID: 28837246 Free PMC article.
Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease.
Ihara S, Hirata Y, Hikiba Y, Yamashita A, Tsuboi M, Hata M, Konishi M, Suzuki N, Sakitani K, Kinoshita H, Hayakawa Y, Nakagawa H, Ijichi H, Tateishi K, Koike K. Ihara S, et al. J Crohns Colitis. 2018 Nov 9;12(10):1219-1231. doi: 10.1093/ecco-jcc/jjy088. J Crohns Colitis. 2018. PMID: 29917067
444 results