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Human-relevant near-organ neuromodulation of the immune system via the splenic nerve.
Donegà M, Fjordbakk CT, Kirk J, Sokal DM, Gupta I, Hunsberger GE, Crawford A, Cook S, Viscasillas J, Stathopoulou TR, Miranda JA, Dopson WJ, Goodwin D, Rowles A, McGill P, McSloy A, Werling D, Witherington J, Chew DJ, Perkins JD. Donegà M, et al. Among authors: perkins jd. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2025428118. doi: 10.1073/pnas.2025428118. Proc Natl Acad Sci U S A. 2021. PMID: 33972441 Free PMC article.
Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves.
Gupta I, Cassará AM, Tarotin I, Donega M, Miranda JA, Sokal DM, Ouchouche S, Dopson W, Matteucci P, Neufeld E, Schiefer MA, Rowles A, McGill P, Perkins J, Dolezalova N, Saeb-Parsy K, Kuster N, Yazicioglu RF, Witherington J, Chew DJ. Gupta I, et al. Commun Biol. 2020 Oct 16;3(1):577. doi: 10.1038/s42003-020-01299-0. Commun Biol. 2020. PMID: 33067560 Free PMC article.
Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs.
Sokal DM, McSloy A, Donegà M, Kirk J, Colas RA, Dolezalova N, Gomez EA, Gupta I, Fjordbakk CT, Ouchouche S, Matteucci PB, Schlegel K, Bashirullah R, Werling D, Harman K, Rowles A, Yazicioglu RF, Dalli J, Chew DJ, Perkins JD. Sokal DM, et al. Among authors: perkins jd. Front Immunol. 2021 Mar 29;12:649786. doi: 10.3389/fimmu.2021.649786. eCollection 2021. Front Immunol. 2021. PMID: 33859641 Free PMC article.
The cholinergic anti-inflammatory pathway inhibits inflammation without lymphocyte relay.
Simon T, Kirk J, Dolezalova N, Guyot M, Panzolini C, Bondue A, Lavergne J, Hugues S, Hypolite N, Saeb-Parsy K, Perkins J, Macia E, Sridhar A, Vervoordeldonk MJ, Glaichenhaus N, Donegá M, Blancou P. Simon T, et al. Front Neurosci. 2023 Apr 14;17:1125492. doi: 10.3389/fnins.2023.1125492. eCollection 2023. Front Neurosci. 2023. PMID: 37123375 Free PMC article.
Organotopic organization of the porcine mid-cervical vagus nerve.
Thompson N, Ravagli E, Mastitskaya S, Iacoviello F, Stathopoulou TR, Perkins J, Shearing PR, Aristovich K, Holder D. Thompson N, et al. Front Neurosci. 2023 May 2;17:963503. doi: 10.3389/fnins.2023.963503. eCollection 2023. Front Neurosci. 2023. PMID: 37205051 Free PMC article.
MicroCT optimisation for imaging fascicular anatomy in peripheral nerves.
Thompson N, Ravagli E, Mastitskaya S, Iacoviello F, Aristovich K, Perkins J, Shearing PR, Holder D. Thompson N, et al. J Neurosci Methods. 2020 May 15;338:108652. doi: 10.1016/j.jneumeth.2020.108652. Epub 2020 Mar 13. J Neurosci Methods. 2020. PMID: 32179090 Free PMC article.
399 results