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Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction.
O'Sullivan JF, Leblond AL, Kelly G, Kumar AH, Metharom P, Büneker CK, Alizadeh-Vikali N, Hristova I, Hynes BG, O'Connor R, Caplice NM. O'Sullivan JF, et al. Among authors: caplice nm. Circ Cardiovasc Interv. 2011 Aug;4(4):327-35. doi: 10.1161/CIRCINTERVENTIONS.110.960765. Epub 2011 Jun 28. Circ Cardiovasc Interv. 2011. PMID: 21712526
Bone Marrow-Derived Mesenchymal Stem Cells Have Innate Procoagulant Activity and Cause Microvascular Obstruction Following Intracoronary Delivery: Amelioration by Antithrombin Therapy.
Gleeson BM, Martin K, Ali MT, Kumar AH, Pillai MG, Kumar SP, O'Sullivan JF, Whelan D, Stocca A, Khider W, Barry FP, O'Brien T, Caplice NM. Gleeson BM, et al. Among authors: caplice nm. Stem Cells. 2015 Sep;33(9):2726-37. doi: 10.1002/stem.2050. Epub 2015 Jun 4. Stem Cells. 2015. PMID: 25969127
Randomized placebo controlled trial evaluating the safety and efficacy of single low-dose intracoronary insulin-like growth factor following percutaneous coronary intervention in acute myocardial infarction (RESUS-AMI).
Caplice NM, DeVoe MC, Choi J, Dahly D, Murphy T, Spitzer E, Van Geuns R, Maher MM, Tuite D, Kerins DM, Ali MT, Kalyar I, Fahy EF, Khider W, Kelly P, Kearney PP, Curtin RJ, O'Shea C, Vaughan CJ, Eustace JA, McFadden EP. Caplice NM, et al. Am Heart J. 2018 Jun;200:110-117. doi: 10.1016/j.ahj.2018.03.018. Epub 2018 Apr 3. Am Heart J. 2018. PMID: 29898838 Clinical Trial.
Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1.
Hynes B, Kumar AH, O'Sullivan J, Klein Buneker C, Leblond AL, Weiss S, Schmeckpeper J, Martin K, Caplice NM. Hynes B, et al. Among authors: caplice nm. Eur Heart J. 2013 Mar;34(10):782-9. doi: 10.1093/eurheartj/ehr435. Epub 2011 Dec 15. Eur Heart J. 2013. PMID: 22173909
121 results