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CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors.
Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW. Manfra O, et al. Among authors: melleby ao. Cardiovasc Res. 2022 May 6;118(6):1506-1519. doi: 10.1093/cvr/cvab167. Cardiovasc Res. 2022. PMID: 33970224 Free PMC article.
Overexpression of integrin α11 induces cardiac fibrosis in mice.
Romaine A, Sørensen IW, Zeltz C, Lu N, Erusappan PM, Melleby AO, Zhang L, Bendiksen B, Robinson EL, Aronsen JM, Herum KM, Danielsen HE, Sjaastad I, Christensen G, Gullberg D. Romaine A, et al. Among authors: melleby ao. Acta Physiol (Oxf). 2018 Feb;222(2). doi: 10.1111/apha.12932. Epub 2017 Aug 30. Acta Physiol (Oxf). 2018. PMID: 28771943
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy.
Lunde IG, Aronsen JM, Melleby AO, Strand ME, Skogestad J, Bendiksen BA, Ahmed MS, Sjaastad I, Attramadal H, Carlson CR, Christensen G. Lunde IG, et al. Among authors: melleby ao. Mol Biol Rep. 2022 Dec;49(12):11795-11809. doi: 10.1007/s11033-022-07985-y. Epub 2022 Oct 7. Mol Biol Rep. 2022. PMID: 36205855 Free PMC article.
Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure.
Skogestad J, Albert I, Hougen K, Lothe GB, Lunde M, Eken OS, Veras I, Huynh NTT, Børstad M, Marshall S, Shen X, Louch WE, Robinson EL, Cleveland JC Jr, Ambardekar AV, Schwisow JA, Jonas E, Calejo AI, Morth JP, Taskén K, Melleby AO, Lunde PK, Sjaastad I, Carlson CR, Aronsen JM. Skogestad J, et al. Among authors: melleby ao. Circulation. 2023 Apr 18;147(16):1221-1236. doi: 10.1161/CIRCULATIONAHA.121.054168. Epub 2023 Mar 6. Circulation. 2023. PMID: 36876489
Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction.
Vistnes M, Erusappan PM, Sasi A, Nordén ES, Bergo KK, Romaine A, Lunde IG, Zhang L, Olsen MB, Øgaard J, Carlson CR, Wang CH, Riise J, Dahl CP, Fiane AE, Hauge-Iversen IM, Espe E, Melleby AO, Tønnessen T, Aronsen JM, Sjaastad I, Christensen G. Vistnes M, et al. Among authors: melleby ao. Cardiovasc Res. 2023 Aug 19;119(10):1915-1927. doi: 10.1093/cvr/cvad078. Cardiovasc Res. 2023. PMID: 37216909 Free PMC article.
Regulation of cardiomyocyte t-tubule structure by preload and afterload: Roles in cardiac compensation and decompensation.
Ruud M, Frisk M, Melleby AO, Norseng PA, Mohamed BA, Li J, Aronsen JM, Setterberg IE, Jakubiczka J, van Hout I, Coffey S, Shen X, Nygård S, Lunde IG, Tønnessen T, Jones PP, Sjaastad I, Gullestad L, Toischer K, Dahl CP, Christensen G, Louch WE. Ruud M, et al. Among authors: melleby ao. J Physiol. 2024 Apr 30. doi: 10.1113/JP284566. Online ahead of print. J Physiol. 2024. PMID: 38686538
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart.
Romaine A, Melleby AO, Alam J, Lobert VH, Lu N, Lockwood FE, Hasic A, Lunde IG, Sjaastad I, Stenmark H, Herum KM, Gullberg D, Christensen G. Romaine A, et al. Among authors: melleby ao. Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H1057-H1071. doi: 10.1152/ajpheart.00635.2021. Epub 2022 May 6. Am J Physiol Heart Circ Physiol. 2022. PMID: 35522553 Free article.
17 results