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A 6-month inhalation toxicology study in Apoe-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Wong ET, Szostak J, Titz B, Lee T, Wong SK, Lavrynenko O, Merg C, Corciulo M, Simicevic J, Auberson M, Peric D, Dulize R, Bornand D, Loh GJ, Lee KM, Zhang J, Miller JH 4th, Schlage WK, Guedj E, Schneider T, Phillips B, Leroy P, Choukrallah MA, Sierro N, Buettner A, Xiang Y, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Wong ET, et al. Among authors: lee t, lee km. Arch Toxicol. 2021 May;95(5):1805-1829. doi: 10.1007/s00204-021-03020-4. Epub 2021 May 7. Arch Toxicol. 2021. PMID: 33963423 Free PMC article.
A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.
Phillips BW, Schlage WK, Titz B, Kogel U, Sciuscio D, Martin F, Leroy P, Vuillaume G, Krishnan S, Lee T, Veljkovic E, Elamin A, Merg C, Ivanov NV, Peitsch MC, Hoeng J, Vanscheeuwijck P. Phillips BW, et al. Among authors: lee t. Food Chem Toxicol. 2018 Jun;116(Pt B):388-413. doi: 10.1016/j.fct.2018.04.015. Epub 2018 Apr 11. Food Chem Toxicol. 2018. PMID: 29654848 Free article.
A 6-month systems toxicology inhalation study in ApoE-/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke.
Szostak J, Wong ET, Titz B, Lee T, Wong SK, Low T, Lee KM, Zhang J, Kumar A, Schlage WK, Guedj E, Phillips B, Leroy P, Buettner A, Xiang Y, Martin F, Sewer A, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Szostak J, et al. Among authors: lee t, lee km. Am J Physiol Heart Circ Physiol. 2020 Mar 1;318(3):H604-H631. doi: 10.1152/ajpheart.00613.2019. Epub 2020 Jan 24. Am J Physiol Heart Circ Physiol. 2020. PMID: 31975625 Free article.
Evaluation of toxicity of aerosols from flavored e-liquids in Sprague-Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.
Ho J, Sciuscio D, Kogel U, Titz B, Leroy P, Vuillaume G, Talikka M, Martin E, Pospisil P, Lebrun S, Xia W, Lee T, Chng YX, Phillips BW, Veljkovic E, Guedj E, Xiang Y, Ivanov NV, Peitsch MC, Hoeng J, Vanscheeuwijck P. Ho J, et al. Among authors: lee t. Arch Toxicol. 2020 Jun;94(6):2179-2206. doi: 10.1007/s00204-020-02759-6. Epub 2020 May 5. Arch Toxicol. 2020. PMID: 32367274 Free PMC article.
Simple prediction tools for disease progression in unvaccinated patients with mild/moderate COVID-19 aged under 65 years: Simplified DOATS and DOAT scores.
Shibata Y, Minemura H, Suzuki Y, Nikaido T, Tanino Y, Rikimaru M, Kawamata T, Togawa R, Sato Y, Saito J, Kanazawa K, Iseki K; Doctors in Fukushima and Yamagata against COVID-19. Shibata Y, et al. Respir Investig. 2024 May 22;62(4):681-684. doi: 10.1016/j.resinv.2024.05.006. Online ahead of print. Respir Investig. 2024. PMID: 38781788
Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms.
Citarella BW, Kartsonaki C, Ibáñez-Prada ED, Gonçalves BP, Baruch J, Escher M, Pritchard MG, Wei J, Philippy F, Dagens A, Hall M, Lee J, Kutsogiannis DJ, Wils EJ, Fernandes MA, Tirupakuzhi Vijayaraghavan BK, Panda PK, Martin-Loeches I, Ohshimo S, Fatoni AZ, Horby P, Dunning J, Rello J, Merson L, Rojek A, Vaillant M, Olliaro P, Reyes LF; ISARIC Clinical Characterisation Group. Citarella BW, et al. Heliyon. 2024 May 4;10(10):e29591. doi: 10.1016/j.heliyon.2024.e29591. eCollection 2024 May 30. Heliyon. 2024. PMID: 38779000 Free PMC article.
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