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Cellular pathways of recombinant adeno-associated virus production for gene therapy.
Sha S, Maloney AJ, Katsikis G, Nguyen TNT, Neufeld C, Wolfrum J, Barone PW, Springs SL, Manalis SR, Sinskey AJ, Braatz RD. Sha S, et al. Among authors: braatz rd. Biotechnol Adv. 2021 Jul-Aug;49:107764. doi: 10.1016/j.biotechadv.2021.107764. Epub 2021 May 3. Biotechnol Adv. 2021. PMID: 33957276 Review.
Modeling of copy number variability in Pichia pastoris.
Lu AE, Maloney AJ, Dalvie NC, Brady JR, Love KR, Love JC, Braatz RD. Lu AE, et al. Among authors: braatz rd. Biotechnol Bioeng. 2021 May;118(5):1832-1839. doi: 10.1002/bit.27698. Epub 2021 Feb 19. Biotechnol Bioeng. 2021. PMID: 33527350
Analytical methods for process and product characterization of recombinant adeno-associated virus-based gene therapies.
Gimpel AL, Katsikis G, Sha S, Maloney AJ, Hong MS, Nguyen TNT, Wolfrum J, Springs SL, Sinskey AJ, Manalis SR, Barone PW, Braatz RD. Gimpel AL, et al. Among authors: braatz rd. Mol Ther Methods Clin Dev. 2021 Feb 17;20:740-754. doi: 10.1016/j.omtm.2021.02.010. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2021. PMID: 33738328 Free PMC article. Review.
Mechanistic modeling of viral particle production.
Canova CT, Inguva PK, Braatz RD. Canova CT, et al. Among authors: braatz rd. Biotechnol Bioeng. 2023 Mar;120(3):629-641. doi: 10.1002/bit.28296. Epub 2022 Dec 22. Biotechnol Bioeng. 2023. PMID: 36461898 Review.
Mechanistic modeling explains the production dynamics of recombinant adeno-associated virus with the baculovirus expression vector system.
Destro F, Joseph J, Srinivasan P, Kanter JM, Neufeld C, Wolfrum JM, Barone PW, Springs SL, Sinskey AJ, Cecchini S, Kotin RM, Braatz RD. Destro F, et al. Among authors: braatz rd. Mol Ther Methods Clin Dev. 2023 Jun 2;30:122-146. doi: 10.1016/j.omtm.2023.05.019. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37746245 Free PMC article.
Analysis of Poly(ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a surface crowding model.
Zhong-Johnson EZL, Dong Z, Canova CT, Destro F, Cañellas M, Hoffman MC, Maréchal J, Johnson TM, Zheng M, Schlau-Cohen GS, Lucas MF, Braatz RD, Sprenger KG, Voigt CA, Sinskey AJ. Zhong-Johnson EZL, et al. Among authors: braatz rd. J Biol Chem. 2024 Mar;300(3):105783. doi: 10.1016/j.jbc.2024.105783. Epub 2024 Feb 22. J Biol Chem. 2024. PMID: 38395309 Free PMC article.
55 results