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Page 1
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.
Youlten SE, Kemp JP, Logan JG, Ghirardello EJ, Sergio CM, Dack MRG, Guilfoyle SE, Leitch VD, Butterfield NC, Komla-Ebri D, Chai RC, Corr AP, Smith JT, Mohanty ST, Morris JA, McDonald MM, Quinn JMW, McGlade AR, Bartonicek N, Jansson M, Hatzikotoulas K, Irving MD, Beleza-Meireles A, Rivadeneira F, Duncan E, Richards JB, Adams DJ, Lelliott CJ, Brink R, Phan TG, Eisman JA, Evans DM, Zeggini E, Baldock PA, Bassett JHD, Williams GR, Croucher PI. Youlten SE, et al. Among authors: mcdonald mm. Nat Commun. 2021 May 5;12(1):2444. doi: 10.1038/s41467-021-22517-1. Nat Commun. 2021. PMID: 33953184 Free PMC article.
Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis.
Baldock PA, Allison SJ, Lundberg P, Lee NJ, Slack K, Lin EJ, Enriquez RF, McDonald MM, Zhang L, During MJ, Little DG, Eisman JA, Gardiner EM, Yulyaningsih E, Lin S, Sainsbury A, Herzog H. Baldock PA, et al. Among authors: mcdonald mm. J Biol Chem. 2007 Jun 29;282(26):19092-102. doi: 10.1074/jbc.M700644200. Epub 2007 May 9. J Biol Chem. 2007. PMID: 17491016 Free article.
Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight.
Baldock PA, Lee NJ, Driessler F, Lin S, Allison S, Stehrer B, Lin EJ, Zhang L, Enriquez RF, Wong IP, McDonald MM, During M, Pierroz DD, Slack K, Shi YC, Yulyaningsih E, Aljanova A, Little DG, Ferrari SL, Sainsbury A, Eisman JA, Herzog H. Baldock PA, et al. Among authors: mcdonald mm. PLoS One. 2009 Dec 22;4(12):e8415. doi: 10.1371/journal.pone.0008415. PLoS One. 2009. PMID: 20027231 Free PMC article.
Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.
Lawson MA, McDonald MM, Kovacic N, Hua Khoo W, Terry RL, Down J, Kaplan W, Paton-Hough J, Fellows C, Pettitt JA, Neil Dear T, Van Valckenborgh E, Baldock PA, Rogers MJ, Eaton CL, Vanderkerken K, Pettit AR, Quinn JM, Zannettino AC, Phan TG, Croucher PI. Lawson MA, et al. Among authors: mcdonald mm. Nat Commun. 2015 Dec 3;6:8983. doi: 10.1038/ncomms9983. Nat Commun. 2015. PMID: 26632274 Free PMC article.
Bone metastasis: the importance of the neighbourhood.
Croucher PI, McDonald MM, Martin TJ. Croucher PI, et al. Among authors: mcdonald mm. Nat Rev Cancer. 2016 May 25;16(6):373-86. doi: 10.1038/nrc.2016.44. Nat Rev Cancer. 2016. PMID: 27220481 Review.
The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis.
Fairfield H, Falank C, Harris E, Demambro V, McDonald M, Pettitt JA, Mohanty ST, Croucher P, Kramer I, Kneissel M, Rosen CJ, Reagan MR. Fairfield H, et al. J Cell Physiol. 2018 Feb;233(2):1156-1167. doi: 10.1002/jcp.25976. Epub 2017 Jun 6. J Cell Physiol. 2018. PMID: 28460416 Free PMC article.
Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma.
McDonald MM, Reagan MR, Youlten SE, Mohanty ST, Seckinger A, Terry RL, Pettitt JA, Simic MK, Cheng TL, Morse A, Le LMT, Abi-Hanna D, Kramer I, Falank C, Fairfield H, Ghobrial IM, Baldock PA, Little DG, Kneissel M, Vanderkerken K, Bassett JHD, Williams GR, Oyajobi BO, Hose D, Phan TG, Croucher PI. McDonald MM, et al. Blood. 2017 Jun 29;129(26):3452-3464. doi: 10.1182/blood-2017-03-773341. Epub 2017 May 17. Blood. 2017. PMID: 28515094 Free PMC article.
120 results