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Improving Right Ventricular Function by Increasing BMP Signaling with FK506.
Boehm M, Tian X, Ali MK, Mao Y, Ichimura K, Zhao M, Kuramoto K, Dannewitz Prosseda S, Fajardo G, Dufva MJ, Qin X, Kheyfets VO, Bernstein D, Reddy S, Metzger RJ, Zamanian RT, Haddad F, Spiekerkoetter E. Boehm M, et al. Among authors: reddy s. Am J Respir Cell Mol Biol. 2021 Sep;65(3):272-287. doi: 10.1165/rcmb.2020-0528OC. Am J Respir Cell Mol Biol. 2021. PMID: 33938785 Free PMC article.
Altered ubiquitin-proteasome signaling in right ventricular hypertrophy and failure.
Rajagopalan V, Zhao M, Reddy S, Fajardo G, Wang X, Dewey S, Gomes AV, Bernstein D. Rajagopalan V, et al. Among authors: reddy s. Am J Physiol Heart Circ Physiol. 2013 Aug 15;305(4):H551-62. doi: 10.1152/ajpheart.00771.2012. Epub 2013 May 31. Am J Physiol Heart Circ Physiol. 2013. PMID: 23729213 Free PMC article.
FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.
Spiekerkoetter E, Tian X, Cai J, Hopper RK, Sudheendra D, Li CG, El-Bizri N, Sawada H, Haghighat R, Chan R, Haghighat L, de Jesus Perez V, Wang L, Reddy S, Zhao M, Bernstein D, Solow-Cordero DE, Beachy PA, Wandless TJ, Ten Dijke P, Rabinovitch M. Spiekerkoetter E, et al. Among authors: reddy s. J Clin Invest. 2013 Aug;123(8):3600-13. doi: 10.1172/JCI65592. Epub 2013 Jul 15. J Clin Invest. 2013. PMID: 23867624 Free PMC article.
BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension.
Diebold I, Hennigs JK, Miyagawa K, Li CG, Nickel NP, Kaschwich M, Cao A, Wang L, Reddy S, Chen PI, Nakahira K, Alcazar MA, Hopper RK, Ji L, Feldman BJ, Rabinovitch M. Diebold I, et al. Among authors: reddy s. Cell Metab. 2015 Apr 7;21(4):596-608. doi: 10.1016/j.cmet.2015.03.010. Cell Metab. 2015. PMID: 25863249 Free PMC article.
The vulnerable right ventricle.
Reddy S, Bernstein D. Reddy S, et al. Curr Opin Pediatr. 2015 Oct;27(5):563-8. doi: 10.1097/MOP.0000000000000268. Curr Opin Pediatr. 2015. PMID: 26262580 Free PMC article. Review.
Molecular Mechanisms of Right Ventricular Failure.
Reddy S, Bernstein D. Reddy S, et al. Circulation. 2015 Nov 3;132(18):1734-42. doi: 10.1161/CIRCULATIONAHA.114.012975. Circulation. 2015. PMID: 26527692 Free PMC article. Review.
Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulation.
Jung G, Fajardo G, Ribeiro AJ, Kooiker KB, Coronado M, Zhao M, Hu DQ, Reddy S, Kodo K, Sriram K, Insel PA, Wu JC, Pruitt BL, Bernstein D. Jung G, et al. Among authors: reddy s. FASEB J. 2016 Apr;30(4):1464-79. doi: 10.1096/fj.15-280982. Epub 2015 Dec 16. FASEB J. 2016. PMID: 26675706 Free PMC article.
We propose that assessment of signaling be added to the indices of phenotypic maturation of hiPSC-CMs.-Jung, G., Fajardo, G., Ribeiro, A. J. S., Kooiker, K. B., Coronado, M., Zhao, M., Hu, D.-Q., Reddy, S., Kodo, K., Sriram, K., Insel, P. ...
We propose that assessment of signaling be added to the indices of phenotypic maturation of hiPSC-CMs.-Jung, G., Fajardo, G., Ribeiro, A. J. …
5,158 results