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G protein β5-ATM complexes drive acetaminophen-induced hepatotoxicity.
Pramanick A, Chakraborti S, Mahata T, Basak M, Das K, Verma SK, Sengar AS, Singh PK, Kumar P, Bhattacharya B, Biswas S, Pal PB, Sarkar S, Agrawal V, Saha S, Nath D, Chatterjee S, Stewart A, Maity B. Pramanick A, et al. Among authors: kumar p. Redox Biol. 2021 Jul;43:101965. doi: 10.1016/j.redox.2021.101965. Epub 2021 Apr 28. Redox Biol. 2021. PMID: 33933881 Free PMC article.
5H-benzo[h]thiazolo[2,3-b]quinazolines ameliorate NDEA-induced hepatocellular carcinogenesis in rats through IL-6 downregulation along with oxidative and metabolic stress reduction.
Keshari AK, Singh AK, Kumar U, Raj V, Rai A, Kumar P, Kumar D, Maity B, Nath S, Prakash A, Saha S. Keshari AK, et al. Among authors: kumar u, kumar d, kumar p. Drug Des Devel Ther. 2017 Oct 13;11:2981-2995. doi: 10.2147/DDDT.S143075. eCollection 2017. Drug Des Devel Ther. 2017. PMID: 29075102 Free PMC article.
Novel 1,4-benzothazines obliterate COX-2 mediated JAK-2/STAT-3 signals with potential regulation of oxidative and metabolic stress during colorectal cancer.
Rai A, Kumar U, Raj V, Singh AK, Kumar P, Keshari AK, Kumar D, Maity B, De A, Samanta A, Nath S, Prakash A, Gosipatala SB, Chand G, Saha S. Rai A, et al. Among authors: kumar u, kumar d, kumar p. Pharmacol Res. 2018 Jun;132:188-203. doi: 10.1016/j.phrs.2017.12.010. Epub 2017 Dec 8. Pharmacol Res. 2018. PMID: 29229353
6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid attenuates colon carcinogenesis via blockade of IL-6 mediated signals.
Mishra P, Raj V, Bhadauria AS, Singh AK, Rai A, Kumar P, Keshari AK, De A, Samanta A, Kumar U, Kumar D, Maity B, Nath S, Prakash A, Ansari KM, Saha S. Mishra P, et al. Among authors: kumar u, kumar d, kumar p. Biomed Pharmacother. 2018 Apr;100:282-295. doi: 10.1016/j.biopha.2018.02.009. Epub 2018 Feb 16. Biomed Pharmacother. 2018. PMID: 29448205
Novel 1,3,4-thiadiazoles inhibit colorectal cancer via blockade of IL-6/COX-2 mediated JAK2/STAT3 signals as evidenced through data-based mathematical modeling.
Raj V, Bhadauria AS, Singh AK, Kumar U, Rai A, Keshari AK, Kumar P, Kumar D, Maity B, Nath S, Prakash A, Ansari KM, Jat JL, Saha S. Raj V, et al. Among authors: kumar u, kumar d, kumar p. Cytokine. 2019 Jun;118:144-159. doi: 10.1016/j.cyto.2018.03.026. Epub 2018 Mar 23. Cytokine. 2019. PMID: 29580751
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