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Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer.
Gambaro K, Marques M, McNamara S, Couetoux du Tertre M, Diaz Z, Hoffert C, Srivastava A, Hébert S, Samson B, Lespérance B, Ko YJ, Dalfen R, St-Hilaire E, Sideris L, Couture F, Burkes R, Harb M, Camlioglu E, Gologan A, Pelsser V, Constantin A, Greenwood CMT, Tejpar S, Kavan P, Kleinman CL, Batist G. Gambaro K, et al. Among authors: kleinman cl. Clin Transl Med. 2021 Apr;11(4):e401. doi: 10.1002/ctm2.401. Clin Transl Med. 2021. PMID: 33931971 Free PMC article.
Gene networks show associations with seed region connectivity.
Forest M, Iturria-Medina Y, Goldman JS, Kleinman CL, Lovato A, Oros Klein K, Evans A, Ciampi A, Labbe A, Greenwood CMT. Forest M, et al. Among authors: kleinman cl. Hum Brain Mapp. 2017 Jun;38(6):3126-3140. doi: 10.1002/hbm.23579. Epub 2017 Mar 21. Hum Brain Mapp. 2017. PMID: 28321948 Free PMC article.
SWI/SNF-Compromised Cancers Are Susceptible to Bromodomain Inhibitors.
Shorstova T, Marques M, Su J, Johnston J, Kleinman CL, Hamel N, Huang S, Alaoui-Jamali MA, Foulkes WD, Witcher M. Shorstova T, et al. Among authors: kleinman cl. Cancer Res. 2019 May 15;79(10):2761-2774. doi: 10.1158/0008-5472.CAN-18-1545. Epub 2019 Mar 15. Cancer Res. 2019. PMID: 30877105
Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas.
Khan A, Gamble LD, Upton DH, Ung C, Yu DMT, Ehteda A, Pandher R, Mayoh C, Hébert S, Jabado N, Kleinman CL, Burns MR, Norris MD, Haber M, Tsoli M, Ziegler DS. Khan A, et al. Among authors: kleinman cl. Nat Commun. 2021 Feb 12;12(1):971. doi: 10.1038/s41467-021-20896-z. Nat Commun. 2021. PMID: 33579942 Free PMC article.
3D chromatin remodeling potentiates transcriptional programs driving cell invasion.
Lebeau B, Jangal M, Zhao T, Wong CK, Wong N, Cañedo EC, Hébert S, Aguilar-Mahecha A, Chabot C, Buchanan M, Catterall R, McCaffrey L, Deblois G, Kleinman C, Park M, Basik M, Witcher M. Lebeau B, et al. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2203452119. doi: 10.1073/pnas.2203452119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037342 Free PMC article.
80 results