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The German Network for Personalized Medicine to enhance patient care and translational research.
Illert AL, Stenzinger A, Bitzer M, Horak P, Gaidzik VI, Möller Y, Beha J, Öner Ö, Schmitt F, Laßmann S, Ossowski S, Schaaf CP, Hallek M, Brümmendorf TH, Albers P, Fehm T, Brossart P, Glimm H, Schadendorf D, Bleckmann A, Brandts CH, Esposito I, Mack E, Peters C, Bokemeyer C, Fröhling S, Kindler T, Algül H, Heinemann V, Döhner H, Bargou R, Ellenrieder V, Hillemanns P, Lordick F, Hochhaus A, Beckmann MW, Pukrop T, Trepel M, Sundmacher L, Wesselmann S, Nettekoven G, Kohlhuber F, Heinze O, Budczies J, Werner M, Nikolaou K, Beer AJ, Tabatabai G, Weichert W, Keilholz U, Boerries M, Kohlbacher O, Duyster J, Thimme R, Seufferlein T, Schirmacher P, Malek NP. Illert AL, et al. Among authors: pukrop t. Nat Med. 2023 Jun;29(6):1298-1301. doi: 10.1038/s41591-023-02354-z. Nat Med. 2023. PMID: 37280276 No abstract available.
LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer.
Blazquez R, Rietkötter E, Wenske B, Wlochowitz D, Sparrer D, Vollmer E, Müller G, Seegerer J, Sun X, Dettmer K, Barrantes-Freer A, Stange L, Utpatel K, Bleckmann A, Treiber H, Bohnenberger H, Lenz C, Schulz M, Reimelt C, Hackl C, Grade M, Büyüktas D, Siam L, Balkenhol M, Stadelmann C, Kube D, Krahn MP, Proescholdt MA, Riemenschneider MJ, Evert M, Oefner PJ, Klein CA, Hanisch UK, Binder C, Pukrop T. Blazquez R, et al. Among authors: pukrop t. Int J Cancer. 2020 Jun 1;146(11):3170-3183. doi: 10.1002/ijc.32742. Epub 2019 Nov 11. Int J Cancer. 2020. PMID: 31626715 Free article.
The macro-metastasis/organ parenchyma interface (MMPI) - A hitherto unnoticed area.
Blazquez R, Sparrer D, Wendl C, Evert M, Riemenschneider MJ, Krahn MP, Erez N, Proescholdt M, Pukrop T. Blazquez R, et al. Among authors: pukrop t. Semin Cancer Biol. 2020 Feb;60:324-333. doi: 10.1016/j.semcancer.2019.10.012. Epub 2019 Oct 21. Semin Cancer Biol. 2020. PMID: 31647982 Free article. Review.
Coronavirus disease 2019 induces multi-lineage, morphologic changes in peripheral blood cells.
Lüke F, Orsó E, Kirsten J, Poeck H, Grube M, Wolff D, Burkhardt R, Lunz D, Lubnow M, Schmidt B, Hitzenbichler F, Hanses F, Salzberger B, Evert M, Herr W, Brochhausen C, Pukrop T, Reichle A, Heudobler D. Lüke F, et al. Among authors: pukrop t. EJHaem. 2020 Jun 29;1(1):376-383. doi: 10.1002/jha2.44. eCollection 2020 Jul. EJHaem. 2020. PMID: 32838398 Free PMC article.
Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone.
Siska PJ, Decking SM, Babl N, Matos C, Bruss C, Singer K, Klitzke J, Schön M, Simeth J, Köstler J, Siegmund H, Ugele I, Paulus M, Dietl A, Kolodova K, Steines L, Freitag K, Peuker A, Schönhammer G, Raithel J, Graf B, Geismann F, Lubnow M, Mack M, Hau P, Bohr C, Burkhardt R, Gessner A, Salzberger B, Wagner R, Hanses F, Hitzenbichler F, Heudobler D, Lüke F, Pukrop T, Herr W, Wolff D, Spang R, Poeck H, Hoffmann P, Jantsch J, Brochhausen C, Lunz D, Rehli M, Kreutz M, Renner K. Siska PJ, et al. Among authors: pukrop t. J Clin Invest. 2021 Nov 15;131(22):e148225. doi: 10.1172/JCI148225. J Clin Invest. 2021. PMID: 34779418 Free PMC article.
Breakouts-A Radiological Sign of Poor Prognosis in Patients With Brain Metastases.
Blazquez R, Proescholdt MA, Klauser M, Schebesch KM, Doenitz C, Heudobler D, Stange L, Riemenschneider MJ, Bumes E, Rosengarth K, Schicho A, Schmidt NO, Brawanski A, Pukrop T, Wendl C. Blazquez R, et al. Among authors: pukrop t. Front Oncol. 2022 Apr 4;12:849880. doi: 10.3389/fonc.2022.849880. eCollection 2022. Front Oncol. 2022. PMID: 35444944 Free PMC article.
Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain.
Blazquez R, Chuang HN, Wenske B, Trigueros L, Wlochowitz D, Liguori R, Ferrazzi F, Regen T, Proescholdt MA, Rohde V, Riemenschneider MJ, Stadelmann C, Bleckmann A, Beißbarth T, van Rossum D, Hanisch UK, Pukrop T. Blazquez R, et al. Among authors: pukrop t. Oncogene. 2022 Nov;41(46):5008-5019. doi: 10.1038/s41388-022-02496-3. Epub 2022 Oct 12. Oncogene. 2022. PMID: 36224342 Free PMC article.
116 results