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Ovarian Hyperandrogenism and Response to Gonadotropin-releasing Hormone Analogues in Primary Severe Insulin Resistance.
Huang-Doran I, Kinzer AB, Jimenez-Linan M, Thackray K, Harris J, Adams CL, de Kerdanet M, Stears A, O'Rahilly S, Savage DB, Gorden P, Brown RJ, Semple RK. Huang-Doran I, et al. Among authors: stears a. J Clin Endocrinol Metab. 2021 Jul 13;106(8):2367-2383. doi: 10.1210/clinem/dgab275. J Clin Endocrinol Metab. 2021. PMID: 33901270 Free PMC article.
Mitochondrial oxidative phosphorylation is impaired in patients with congenital lipodystrophy.
Sleigh A, Stears A, Thackray K, Watson L, Gambineri A, Nag S, Campi VI, Schoenmakers N, Brage S, Carpenter TA, Murgatroyd PR, O'Rahilly S, Kemp GJ, Savage DB. Sleigh A, et al. Among authors: stears a. J Clin Endocrinol Metab. 2012 Mar;97(3):E438-42. doi: 10.1210/jc.2011-2587. Epub 2012 Jan 11. J Clin Endocrinol Metab. 2012. PMID: 22238385 Free PMC article.
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.
Lotta LA, Gulati P, Day FR, Payne F, Ongen H, van de Bunt M, Gaulton KJ, Eicher JD, Sharp SJ, Luan J, De Lucia Rolfe E, Stewart ID, Wheeler E, Willems SM, Adams C, Yaghootkar H; EPIC-InterAct Consortium; Cambridge FPLD1 Consortium; Forouhi NG, Khaw KT, Johnson AD, Semple RK, Frayling T, Perry JR, Dermitzakis E, McCarthy MI, Barroso I, Wareham NJ, Savage DB, Langenberg C, O'Rahilly S, Scott RA. Lotta LA, et al. Nat Genet. 2017 Jan;49(1):17-26. doi: 10.1038/ng.3714. Epub 2016 Nov 14. Nat Genet. 2017. PMID: 27841877 Free PMC article.
Recent developments in lipodystrophy.
Melvin A, Stears A, Savage DB. Melvin A, et al. Among authors: stears a. Curr Opin Lipidol. 2019 Aug;30(4):284-290. doi: 10.1097/MOL.0000000000000613. Curr Opin Lipidol. 2019. PMID: 31135595 Review.
Describing the natural history of clinical, biochemical and radiological outcomes of children with familial partial lipodystrophy type 2 (FPLD2) from the United Kingdom: A retrospective case series.
Zhong ZX, Harris J, Wilber E, Gorman S, Savage DB, O'Rahilly S, Stears A, Williams RM. Zhong ZX, et al. Among authors: stears a. Clin Endocrinol (Oxf). 2022 Dec;97(6):755-762. doi: 10.1111/cen.14806. Epub 2022 Aug 17. Clin Endocrinol (Oxf). 2022. PMID: 35920656 Free PMC article.
20 results