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Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Zaufel A, van de Wiel SMW, Yin L, Fauler G, Chien D, Dong X, Gilmer JF, Truong JK, Dawson PA, van de Graaf SFJ, Fickert P, Moustafa T. Zaufel A, et al. Among authors: moustafa t. Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1;1867(8):166153. doi: 10.1016/j.bbadis.2021.166153. Epub 2021 Apr 22. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33895309 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35560809
Targeting nuclear bile acid receptors for liver disease.
Trauner M, Baghdasaryan A, Claudel T, Fickert P, Halilbasic E, Moustafa T, Zollner G. Trauner M, et al. Among authors: moustafa t. Dig Dis. 2011;29(1):98-102. doi: 10.1159/000324141. Epub 2011 Jun 17. Dig Dis. 2011. PMID: 21691114 Review.
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Moustafa T, Fickert P, Magnes C, Guelly C, Thueringer A, Frank S, Kratky D, Sattler W, Reicher H, Sinner F, Gumhold J, Silbert D, Fauler G, Höfler G, Lass A, Zechner R, Trauner M. Moustafa T, et al. Gastroenterology. 2012 Jan;142(1):140-151.e12. doi: 10.1053/j.gastro.2011.09.051. Epub 2011 Oct 14. Gastroenterology. 2012. PMID: 22001865
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Zollner G, Wagner M, Moustafa T, Fickert P, Silbert D, Gumhold J, Fuchsbichler A, Halilbasic E, Denk H, Marschall HU, Trauner M. Zollner G, et al. Among authors: moustafa t. Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G923-32. doi: 10.1152/ajpgi.00490.2005. Epub 2005 Dec 15. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16357057 Free article.
Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.
Fickert P, Krones E, Pollheimer MJ, Thueringer A, Moustafa T, Silbert D, Halilbasic E, Yang M, Jaeschke H, Stokman G, Wells RG, Eller K, Rosenkranz AR, Eggertsen G, Wagner CA, Langner C, Denk H, Trauner M. Fickert P, et al. Among authors: moustafa t. Hepatology. 2013 Dec;58(6):2056-69. doi: 10.1002/hep.26599. Epub 2013 Oct 15. Hepatology. 2013. PMID: 23813550
57 results