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Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Zaufel A, van de Wiel SMW, Yin L, Fauler G, Chien D, Dong X, Gilmer JF, Truong JK, Dawson PA, van de Graaf SFJ, Fickert P, Moustafa T. Zaufel A, et al. Among authors: dong x. Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1;1867(8):166153. doi: 10.1016/j.bbadis.2021.166153. Epub 2021 Apr 22. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33895309 Free PMC article.
A group of cationic amphiphilic drugs activates MRGPRX2 and induces scratching behavior in mice.
Wolf K, Kühn H, Boehm F, Gebhardt L, Glaudo M, Agelopoulos K, Ständer S, Ectors P, Zahn D, Riedel YK, Thimm D, Müller CE, Kretschmann S, Kremer AN, Chien D, Limjunyawong N, Peng Q, Dong X, Kolkhir P, Scheffel J, Søgaard ML, Weigmann B, Neurath MF, Hawro T, Metz M, Fischer MJM, Kremer AE. Wolf K, et al. Among authors: dong x. J Allergy Clin Immunol. 2021 Aug;148(2):506-522.e8. doi: 10.1016/j.jaci.2020.12.655. Epub 2021 Feb 20. J Allergy Clin Immunol. 2021. PMID: 33617860
Cholestatic pruritus: Emerging mechanisms and therapeutics.
Patel SP, Vasavda C, Ho B, Meixiong J, Dong X, Kwatra SG. Patel SP, et al. Among authors: dong x. J Am Acad Dermatol. 2019 Dec;81(6):1371-1378. doi: 10.1016/j.jaad.2019.04.035. Epub 2019 Apr 19. J Am Acad Dermatol. 2019. PMID: 31009666 Free PMC article.
Peripheral mechanisms of itch.
McNeil B, Dong X. McNeil B, et al. Among authors: dong x. Neurosci Bull. 2012 Apr;28(2):100-10. doi: 10.1007/s12264-012-1202-1. Neurosci Bull. 2012. PMID: 22466121 Free PMC article. Review.
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