Sun H - Search Results

1

Phase I/Ib Clinical Trial of Sabatolimab, an Anti-TIM-3 Antibody, Alone and in Combination with Spartalizumab, an Anti-PD-1 Antibody, in Advanced Solid Tumors.

Curigliano G, Gelderblom H, Mach N, Doi T, Tai D, Forde PM, Sarantopoulos J, Bedard PL, Lin CC, Hodi FS, Wilgenhof S, Santoro A, Sabatos-Peyton CA, Longmire TA, Xyrafas A, Sun H, Gutzwiller S, Manenti L, Naing A. Curigliano G, et al. Among authors: sun h. Clin Cancer Res. 2021 Jul 1;27(13):3620-3629. doi: 10.1158/1078-0432.CCR-20-4746. Epub 2021 Apr 21. Clin Cancer Res. 2021. PMID: 33883177 Free article. Clinical Trial.

2

A first-in-human phase 1 dose escalation study of spartalizumab (PDR001), an anti-PD-1 antibody, in patients with advanced solid tumors.

Naing A, Gainor JF, Gelderblom H, Forde PM, Butler MO, Lin CC, Sharma S, Ochoa de Olza M, Varga A, Taylor M, Schellens JHM, Wu H, Sun H, Silva AP, Faris J, Mataraza J, Cameron S, Bauer TM. Naing A, et al. Among authors: sun h. J Immunother Cancer. 2020 Mar;8(1):e000530. doi: 10.1136/jitc-2020-000530. J Immunother Cancer. 2020. PMID: 32179633 Free PMC article. Clinical Trial.

3

Phase Ib study of sabatolimab (MBG453), a novel immunotherapy targeting TIM-3 antibody, in combination with decitabine or azacitidine in high- or very high-risk myelodysplastic syndromes.

Brunner AM, Esteve J, Porkka K, Knapper S, Traer E, Scholl S, Garcia-Manero G, Vey N, Wermke M, Janssen JJWM, Narayan R, Fleming S, Loo S, Tovar N, Kontro M, Ottmann OG, Naidu P, Sun H, Han M, White R, Zhang N, Mohammed A, Sabatos-Peyton CA, Steensma DP, Rinne ML, Borate UM, Wei AH. Brunner AM, et al. Among authors: sun h. Am J Hematol. 2024 Feb;99(2):E32-E36. doi: 10.1002/ajh.27161. Epub 2023 Nov 22. Am J Hematol. 2024. PMID: 37994196 Clinical Trial.

4

Pharmacokinetics and Pharmacodynamics of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis.

Sun H, Van LM, Floch D, Jiang X, Klein UR, Abrams K, Sunkara G. Sun H, et al. J Clin Pharmacol. 2016 Dec;56(12):1516-1527. doi: 10.1002/jcph.754. Epub 2016 Jun 8. J Clin Pharmacol. 2016. PMID: 27119439 Clinical Trial.

5

Bioequivalence of Canakinumab Injected Subcutaneously via an Autoinjector Device or a Prefilled Safety Syringe Device in Healthy Subjects.

Anumolu SS, Lindgren S, Vemula J, Floch D, Reynolds C, Wallny HJ, Sun H. Anumolu SS, et al. Among authors: sun h. Clin Pharmacol Drug Dev. 2018 Nov;7(8):829-836. doi: 10.1002/cpdd.455. Epub 2018 Apr 20. Clin Pharmacol Drug Dev. 2018. PMID: 29676864 Clinical Trial.

6

Sabatolimab (MBG453) model-informed drug development for dose selection in patients with myelodysplastic syndrome/acute myeloid leukemia and solid tumors.

Xu S, Zhang N, Rinne ML, Sun H, Stein AM. Xu S, et al. Among authors: sun h. CPT Pharmacometrics Syst Pharmacol. 2023 Nov;12(11):1653-1665. doi: 10.1002/psp4.12962. Epub 2023 May 31. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37186155 Free PMC article.

7

An Exposure-Response Modeling Approach to Examine the Relationship Between Potency of CYP3A Inducer and Plasma 4β-Hydroxycholesterol in Healthy Subjects.

Jiang X, Dutreix C, Jarugula V, Rebello S, Won CS, Sun H. Jiang X, et al. Among authors: sun h. Clin Pharmacol Drug Dev. 2017 Jan;6(1):19-26. doi: 10.1002/cpdd.267. Epub 2016 Jun 10. Clin Pharmacol Drug Dev. 2017. PMID: 27138546 Clinical Trial.

8

Single-dose pharmacokinetics, safety, and tolerability of albinterferon alfa-2b in subjects with end-stage renal disease on hemodialysis compared to those in matched healthy volunteers.

Serra DB, Sun H, Karwowska S, Praestgaard J, Halabi A, Stein DS. Serra DB, et al. Among authors: sun h. Antimicrob Agents Chemother. 2011 Feb;55(2):473-7. doi: 10.1128/AAC.00626-10. Epub 2010 Nov 22. Antimicrob Agents Chemother. 2011. PMID: 21098255 Free PMC article. Clinical Trial.

9

An Open-Label Study of the Impact of Hepatic Impairment on the Pharmacokinetics and Safety of Single Oral and Intravenous Doses of Omadacycline.

Kovacs SJ, Ting L, Praestgaard J, Sunkara G, Sun H, Stein DS, Tanaka SK, Villano S. Kovacs SJ, et al. Among authors: sun h. Antimicrob Agents Chemother. 2020 Oct 20;64(11):e01650-20. doi: 10.1128/AAC.01650-20. Print 2020 Oct 20. Antimicrob Agents Chemother. 2020. PMID: 32839218 Free PMC article.

10

A First-in-Human Study To Assess the Safety and Pharmacokinetics of LYS228, a Novel Intravenous Monobactam Antibiotic in Healthy Volunteers.

Osborn M, Stachulski N, Sun H, Blais J, Venishetty V, Raccuglia M, Kankam M, Colvin R, Segal F. Osborn M, et al. Among authors: sun h. Antimicrob Agents Chemother. 2019 Jun 24;63(7):e02592-18. doi: 10.1128/AAC.02592-18. Print 2019 Jul. Antimicrob Agents Chemother. 2019. PMID: 31061156 Free PMC article.

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