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A Modular Synthetic Route Involving N-Aryl-2-nitrosoaniline Intermediates Leads to a New Series of 3-Substituted Halogenated Phenazine Antibacterial Agents.
J Med Chem. 2021 Jun 10;64(11):7275-7295. doi: 10.1021/acs.jmedchem.1c00168. Epub 2021 Apr 21.
J Med Chem. 2021.
PMID: 33881312
Free PMC article.
Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival.
Pestoni JC, Klingeman Plati S, Valdivia Camacho OD, Fuse MA, Onatunde M, Sparrow NA, Karajannis MA, Fernández-Valle C, Franco MC.
Pestoni JC, et al. Among authors: fuse ma.
J Biol Chem. 2019 Jul 26;294(30):11354-11368. doi: 10.1074/jbc.RA118.007152. Epub 2019 Jun 6.
J Biol Chem. 2019.
PMID: 31171721
Free PMC article.
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Combination Therapy with c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells.
Fuse MA, Plati SK, Burns SS, Dinh CT, Bracho O, Yan D, Mittal R, Shen R, Soulakova JN, Copik AJ, Liu XZ, Telischi FF, Chang LS, Franco MC, Fernandez-Valle C.
Fuse MA, et al.
Mol Cancer Ther. 2017 Nov;16(11):2387-2398. doi: 10.1158/1535-7163.MCT-17-0417. Epub 2017 Aug 3.
Mol Cancer Ther. 2017.
PMID: 28775147
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Peroxynitrite nitration of Tyr 56 in Hsp90 induces PC12 cell death through P2X7R-dependent PTEN activation.
Jandy M, Noor A, Nelson P, Dennys CN, Karabinas IM, Pestoni JC, Singh GD, Luc L, Devyldere R, Perdomo N, Mitchell CE, Adams L, Fuse MA, Mendoza FA, Marean-Reardon CL, Mehl RA, Estevez AG, Franco MC.
Jandy M, et al. Among authors: fuse ma.
Redox Biol. 2022 Apr;50:102247. doi: 10.1016/j.redox.2022.102247. Epub 2022 Jan 26.
Redox Biol. 2022.
PMID: 35121403
Free PMC article.
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Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development.
Fuse MA, Dinh CT, Vitte J, Kirkpatrick J, Mindos T, Plati SK, Young JI, Huang J, Carlstedt A, Franco MC, Brnjos K, Nagamoto J, Petrilli AM, Copik AJ, Soulakova JN, Bracho O, Yan D, Mittal R, Shen R, Telischi FF, Morrison H, Giovannini M, Liu XZ, Chang LS, Fernandez-Valle C.
Fuse MA, et al.
Neuro Oncol. 2019 Mar 18;21(4):486-497. doi: 10.1093/neuonc/noz002.
Neuro Oncol. 2019.
PMID: 30615146
Free PMC article.
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A chemical biology approach identified PI3K as a potential therapeutic target for neurofibromatosis type 2.
Petrilli AM, Fuse MA, Donnan MS, Bott M, Sparrow NA, Tondera D, Huffziger J, Frenzel C, Malany CS, Echeverri CJ, Smith L, Fernández-Valle C.
Petrilli AM, et al. Among authors: fuse ma.
Am J Transl Res. 2014 Oct 11;6(5):471-93. eCollection 2014.
Am J Transl Res. 2014.
PMID: 25360213
Free PMC article.
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