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PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6.
Johnstone TB, Smith KH, Koziol-White CJ, Li F, Kazarian AG, Corpuz ML, Shumyatcher M, Ehlert FJ, Himes BE, Panettieri RA Jr, Ostrom RS. Johnstone TB, et al. Among authors: corpuz ml. Am J Respir Cell Mol Biol. 2018 Apr;58(4):530-541. doi: 10.1165/rcmb.2017-0294OC. Am J Respir Cell Mol Biol. 2018. PMID: 29262264 Free PMC article.
Transforming Growth Factor-β1 Decreases β2-Agonist-induced Relaxation in Human Airway Smooth Muscle.
Ojiaku CA, Chung E, Parikh V, Williams JK, Schwab A, Fuentes AL, Corpuz ML, Lui V, Paek S, Bexiga NM, Narayan S, Nunez FJ, Ahn K, Ostrom RS, An SS, Panettieri RA Jr. Ojiaku CA, et al. Among authors: corpuz ml. Am J Respir Cell Mol Biol. 2019 Aug;61(2):209-218. doi: 10.1165/rcmb.2018-0301OC. Am J Respir Cell Mol Biol. 2019. PMID: 30742476 Free PMC article.
Budesonide enhances agonist-induced bronchodilation in human small airways by increasing cAMP production in airway smooth muscle.
Koziol-White C, Johnstone TB, Corpuz ML, Cao G, Orfanos S, Parikh V, Deeney B, Tliba O, Ostrom RS, Dainty I, Panettieri RA Jr. Koziol-White C, et al. Among authors: corpuz ml. Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1;318(2):L345-L355. doi: 10.1152/ajplung.00393.2019. Epub 2019 Nov 20. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 31747297 Free PMC article.