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Glucose deprivation-induced aberrant FUT1-mediated fucosylation drives cancer stemness in hepatocellular carcinoma.
J Clin Invest. 2021 Jun 1;131(11):e143377. doi: 10.1172/JCI143377.
J Clin Invest. 2021.
PMID: 33878034
Free PMC article.
A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets.
Liu M, Yan Q, Sun Y, Nam Y, Hu L, Loong JH, Ouyang Q, Zhang Y, Li HL, Kong FE, Li L, Li Y, Li MM, Cheng W, Jiang LX, Fang S, Yang XD, Mo JQ, Gong YF, Tang YQ, Li Y, Yuan YF, Ma NF, Lin G, Ma S, Wang JG, Guan XY.
Liu M, et al. Among authors: loong jh.
Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):6103-6113. doi: 10.1073/pnas.1912146117. Epub 2020 Mar 2.
Proc Natl Acad Sci U S A. 2020.
PMID: 32123069
Free PMC article.
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Lineage tracing and single-cell analysis reveal proliferative Prom1+ tumour-propagating cells and their dynamic cellular transition during liver cancer progression.
Zhou L, Yu KH, Wong TL, Zhang Z, Chan CH, Loong JH, Che N, Yu HJ, Tan KV, Tong M, Ngan ES, Ho JW, Ma S.
Zhou L, et al. Among authors: loong jh.
Gut. 2022 Aug;71(8):1656-1668. doi: 10.1136/gutjnl-2021-324321. Epub 2021 Sep 29.
Gut. 2022.
PMID: 34588223
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The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes.
Kazachenka A, Loong JH, Attig J, Young GR, Ganguli P, Devonshire G, Grehan N; The OCCAMS Consortium; Ciccarelli FD, Fitzgerald RC, Kassiotis G.
Kazachenka A, et al. Among authors: loong jh.
NAR Cancer. 2023 Jul 26;5(3):zcad040. doi: 10.1093/narcan/zcad040. eCollection 2023 Sep.
NAR Cancer. 2023.
PMID: 37502711
Free PMC article.
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SERPINA12 promotes the tumorigenic capacity of HCC stem cells through hyperactivation of AKT/β-catenin signaling.
Yu H, Zhou L, Loong JHC, Lam KH, Wong TL, Ng KY, Tong M, Ma VWS, Wang Y, Zhang X, Lee TK, Yun JP, Yu J, Ma S.
Yu H, et al. Among authors: loong jhc.
Hepatology. 2023 Dec 1;78(6):1711-1726. doi: 10.1097/HEP.0000000000000269. Epub 2023 Jan 13.
Hepatology. 2023.
PMID: 36630996
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Targeting tumor lineage plasticity in hepatocellular carcinoma using an anti-CLDN6 antibody-drug conjugate.
Kong FE, Li GM, Tang YQ, Xi SY, Loong JHC, Li MM, Li HL, Cheng W, Zhu WJ, Mo JQ, Gong YF, Tang H, Zhao Y, Zhang Y, Ma S, Guan XY, Ma NF, Xie MB, Liu M.
Kong FE, et al. Among authors: loong jhc.
Sci Transl Med. 2021 Feb 3;13(579):eabb6282. doi: 10.1126/scitranslmed.abb6282.
Sci Transl Med. 2021.
PMID: 33536280
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PARP inhibitor Olaparib overcomes Sorafenib resistance through reshaping the pluripotent transcriptome in hepatocellular carcinoma.
Yang XD, Kong FE, Qi L, Lin JX, Yan Q, Loong JHC, Xi SY, Zhao Y, Zhang Y, Yuan YF, Ma NF, Ma S, Guan XY, Liu M.
Yang XD, et al. Among authors: loong jhc.
Mol Cancer. 2021 Jan 23;20(1):20. doi: 10.1186/s12943-021-01315-9.
Mol Cancer. 2021.
PMID: 33485358
Free PMC article.
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PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation.
Chan LH, Zhou L, Ng KY, Wong TL, Lee TK, Sharma R, Loong JH, Ching YP, Yuan YF, Xie D, Lo CM, Man K, Artegiani B, Clevers H, Yan HH, Leung SY, Richard S, Guan XY, Huen MSY, Ma S.
Chan LH, et al. Among authors: loong jh.
Cell Rep. 2018 Oct 16;25(3):690-701.e8. doi: 10.1016/j.celrep.2018.09.053.
Cell Rep. 2018.
PMID: 30332648
Free article.
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