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LRRK2 at the pre-synaptic site: A 16-years perspective.
Pischedda F, Piccoli G. Pischedda F, et al. Among authors: piccoli g. J Neurochem. 2021 Apr;157(2):297-311. doi: 10.1111/jnc.15240. Epub 2021 Feb 5. J Neurochem. 2021. PMID: 33206398 Free article. Review.
LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation.
Pischedda F, Cirnaru MD, Ponzoni L, Sandre M, Biosa A, Carrion MP, Marin O, Morari M, Pan L, Greggio E, Bandopadhyay R, Sala M, Piccoli G. Pischedda F, et al. Among authors: piccoli g. Brain. 2021 Jun 22;144(5):1509-1525. doi: 10.1093/brain/awab073. Brain. 2021. PMID: 33876242
The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions.
Carrion MDP, Marsicano S, Daniele F, Marte A, Pischedda F, Di Cairano E, Piovesana E, von Zweydorf F, Kremmer E, Gloeckner CJ, Onofri F, Perego C, Piccoli G. Carrion MDP, et al. Among authors: piccoli g. Sci Rep. 2017 Jul 14;7(1):5377. doi: 10.1038/s41598-017-05760-9. Sci Rep. 2017. PMID: 28710481 Free PMC article.
Levetiracetam treatment ameliorates LRRK2 pathological mutant phenotype.
Rassu M, Biosa A, Galioto M, Fais M, Sini P, Greggio E, Piccoli G, Crosio C, Iaccarino C. Rassu M, et al. Among authors: piccoli g. J Cell Mol Med. 2019 Dec;23(12):8505-8510. doi: 10.1111/jcmm.14674. Epub 2019 Sep 27. J Cell Mol Med. 2019. PMID: 31560168 Free PMC article.
Neurostore: A Novel Cryopreserving Medium for Primary Neurons.
Pischedda F, Piccoli G. Pischedda F, et al. Among authors: piccoli g. Bio Protoc. 2019 Jun 20;9(12):e3270. doi: 10.21769/BioProtoc.3270. eCollection 2019 Jun 20. Bio Protoc. 2019. PMID: 33654789 Free PMC article.
961 results