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Corrigendum to 'A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)'.
Low JL, Lau DP, Zhang X, Kwang XL, Rohatgi N, Chan JV, Chong FT, Wong SQR, Leong HS, Thangavelu MT, Rikka S, Skanderup AMJ, Tan DSW, Periyasamy G, Koh JLY, Iyer NG, DasGupta R. Low JL, et al. Among authors: kwang xl. EBioMedicine. 2021 Apr;66:103297. doi: 10.1016/j.ebiom.2021.103297. Epub 2021 Apr 14. EBioMedicine. 2021. PMID: 33862587 Free PMC article. No abstract available.
A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC).
Low JL, Lau DP, Zhang X, Kwang XL, Rohatgi N, Chan JV, Chong FT, Wong SQR, Leong HS, Thangavelu MT, Rikka S, Skanderup AMJ, Tan DSW, Periyasamy G, Koh JLY, Iyer NG, DasGupta R. Low JL, et al. Among authors: kwang xl. EBioMedicine. 2021 Feb;64:103220. doi: 10.1016/j.ebiom.2021.103220. Epub 2021 Jan 30. EBioMedicine. 2021. PMID: 33529999 Free PMC article.
Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time.
Chia S, Low JL, Zhang X, Kwang XL, Chong FT, Sharma A, Bertrand D, Toh SY, Leong HS, Thangavelu MT, Hwang JSG, Lim KH, Skanthakumar T, Tan HK, Su Y, Hui Choo S, Hentze H, Tan IBH, Lezhava A, Tan P, Tan DSW, Periyasamy G, Koh JLY, Gopalakrishna Iyer N, DasGupta R. Chia S, et al. Among authors: kwang xl. Nat Commun. 2017 Sep 5;8(1):435. doi: 10.1038/s41467-017-00451-5. Nat Commun. 2017. PMID: 28874669 Free PMC article.
Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma.
Tan DSW, Chong FT, Leong HS, Toh SY, Lau DP, Kwang XL, Zhang X, Sundaram GM, Tan GS, Chang MM, Chua BT, Lim WT, Tan EH, Ang MK, Lim TKH, Sampath P, Chowbay B, Skanderup AJ, DasGupta R, Iyer NG. Tan DSW, et al. Among authors: kwang xl. Nat Med. 2017 Oct;23(10):1167-1175. doi: 10.1038/nm.4401. Epub 2017 Sep 18. Nat Med. 2017. PMID: 28920960
Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy.
Sharma A, Cao EY, Kumar V, Zhang X, Leong HS, Wong AML, Ramakrishnan N, Hakimullah M, Teo HMV, Chong FT, Chia S, Thangavelu MT, Kwang XL, Gupta R, Clark JR, Periyasamy G, Iyer NG, DasGupta R. Sharma A, et al. Among authors: kwang xl. Nat Commun. 2018 Nov 22;9(1):4931. doi: 10.1038/s41467-018-07261-3. Nat Commun. 2018. PMID: 30467425 Free PMC article.
Pairing a prognostic target with potential therapeutic strategy for head and neck cancer.
Lek SM, Li K, Tan QX, Shannon NB, Ng WH, Hendrikson J, Tan JWS, Lim HJ, Chen Y, Koh KKN, Skanthakumar T, Kwang XL, Chong FT, Leong HS, Tay G, Putri NE, Lim TKH, Hwang JSG, Ang MK, Tan DSW, Tan NC, Tan HK, Kon OL, Soo KC, Iyer NG, Ong CJ. Lek SM, et al. Among authors: kwang xl. Oral Oncol. 2020 Dec;111:105035. doi: 10.1016/j.oraloncology.2020.105035. Epub 2020 Oct 19. Oral Oncol. 2020. PMID: 33091845 Free article.
Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer.
Lai GGY, Lim TH, Lim J, Liew PJR, Kwang XL, Nahar R, Aung ZW, Takano A, Lee YY, Lau DPX, Tan GS, Tan SH, Tan WL, Ang MK, Toh CK, Tan BS, Devanand A, Too CW, Gogna A, Ong BH, Koh TPT, Kanesvaran R, Ng QS, Jain A, Rajasekaran T, Yuan J, Lim TKH, Lim AST, Hillmer AM, Lim WT, Iyer NG, Tam WL, Zhai W, Tan EH, Tan DSW. Lai GGY, et al. Among authors: kwang xl. J Clin Oncol. 2019 Apr 10;37(11):876-884. doi: 10.1200/JCO.18.00177. Epub 2019 Jan 24. J Clin Oncol. 2019. PMID: 30676858
Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing.
Nahar R, Zhai W, Zhang T, Takano A, Khng AJ, Lee YY, Liu X, Lim CH, Koh TPT, Aung ZW, Lim TKH, Veeravalli L, Yuan J, Teo ASM, Chan CX, Poh HM, Chua IML, Liew AA, Lau DPX, Kwang XL, Toh CK, Lim WT, Lim B, Tam WL, Tan EH, Hillmer AM, Tan DSW. Nahar R, et al. Among authors: kwang xl. Nat Commun. 2018 Jan 15;9(1):216. doi: 10.1038/s41467-017-02584-z. Nat Commun. 2018. PMID: 29335443 Free PMC article.
Bioengineered Hydrogels Recapitulate Fibroblast Heterogeneity in Cancer.
Ho NCW, Yap JYY, Zhao Z, Wang Y, Fernando K, Li CH, Kwang XL, Quah HS, Arcinas C, Iyer NG, Fong ELS. Ho NCW, et al. Among authors: kwang xl. Adv Sci (Weinh). 2024 May;11(20):e2307129. doi: 10.1002/advs.202307129. Epub 2024 Mar 17. Adv Sci (Weinh). 2024. PMID: 38493497