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Page 1
Reconditioning the Neurogenic Niche of Adult Non-human Primates by Antisense Oligonucleotide-Mediated Attenuation of TGFβ Signaling.
Peters S, Kuespert S, Wirkert E, Heydn R, Jurek B, Johannesen S, Hsam O, Korte S, Ludwig FT, Mecklenburg L, Mrowetz H, Altendorfer B, Poupardin R, Petri S, Thal DR, Hermann A, Weishaupt JH, Weis J, Aksoylu IS, Lewandowski SA, Aigner L, Bruun TH, Bogdahn U. Peters S, et al. Among authors: weishaupt jh. Neurotherapeutics. 2021 Jul;18(3):1963-1979. doi: 10.1007/s13311-021-01045-2. Epub 2021 Apr 15. Neurotherapeutics. 2021. PMID: 33860461 Free PMC article.
A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis.
Dupuis L, Dengler R, Heneka MT, Meyer T, Zierz S, Kassubek J, Fischer W, Steiner F, Lindauer E, Otto M, Dreyhaupt J, Grehl T, Hermann A, Winkler AS, Bogdahn U, Benecke R, Schrank B, Wessig C, Grosskreutz J, Ludolph AC; GERP ALS Study Group. Dupuis L, et al. PLoS One. 2012;7(6):e37885. doi: 10.1371/journal.pone.0037885. Epub 2012 Jun 8. PLoS One. 2012. PMID: 22715372 Free PMC article. Clinical Trial.
TDP-43 is intercellularly transmitted across axon terminals.
Feiler MS, Strobel B, Freischmidt A, Helferich AM, Kappel J, Brewer BM, Li D, Thal DR, Walther P, Ludolph AC, Danzer KM, Weishaupt JH. Feiler MS, et al. Among authors: weishaupt jh. J Cell Biol. 2015 Nov 23;211(4):897-911. doi: 10.1083/jcb.201504057. J Cell Biol. 2015. PMID: 26598621 Free PMC article.
Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis.
El Oussini H, Bayer H, Scekic-Zahirovic J, Vercruysse P, Sinniger J, Dirrig-Grosch S, Dieterlé S, Echaniz-Laguna A, Larmet Y, Müller K, Weishaupt JH, Thal DR, van Rheenen W, van Eijk K, Lawson R, Monassier L, Maroteaux L, Roumier A, Wong PC, van den Berg LH, Ludolph AC, Veldink JH, Witting A, Dupuis L. El Oussini H, et al. Among authors: weishaupt jh. Acta Neuropathol. 2016 Mar;131(3):465-80. doi: 10.1007/s00401-016-1534-4. Epub 2016 Jan 7. Acta Neuropathol. 2016. PMID: 26744351 Free article.
Peripheral monocytes are functionally altered and invade the CNS in ALS patients.
Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf WP, Grozdanov V, Thiemann M, Fundel-Clemes K, Freischmidt A, Holzmann K, Strobel B, Weydt P, Witting A, Thal DR, Helferich AM, Hengerer B, Gottschalk KE, Hill O, Kluge M, Ludolph AC, Danzer KM, Weishaupt JH. Zondler L, et al. Among authors: weishaupt jh. Acta Neuropathol. 2016 Sep;132(3):391-411. doi: 10.1007/s00401-016-1548-y. Epub 2016 Feb 24. Acta Neuropathol. 2016. PMID: 26910103
Telomere shortening leads to earlier age of onset in ALS mice.
Linkus B, Wiesner D, Meßner M, Karabatsiakis A, Scheffold A, Rudolph KL, Thal DR, Weishaupt JH, Ludolph AC, Danzer KM. Linkus B, et al. Among authors: weishaupt jh. Aging (Albany NY). 2016 Feb;8(2):382-93. doi: 10.18632/aging.100904. Aging (Albany NY). 2016. PMID: 26978042 Free PMC article.
Alterations in the hypothalamic melanocortin pathway in amyotrophic lateral sclerosis.
Vercruysse P, Sinniger J, El Oussini H, Scekic-Zahirovic J, Dieterlé S, Dengler R, Meyer T, Zierz S, Kassubek J, Fischer W, Dreyhaupt J, Grehl T, Hermann A, Grosskreutz J, Witting A, Van Den Bosch L, Spreux-Varoquaux O; GERP ALS Study Group; Ludolph AC, Dupuis L. Vercruysse P, et al. Brain. 2016 Apr;139(Pt 4):1106-22. doi: 10.1093/brain/aww004. Epub 2016 Mar 16. Brain. 2016. PMID: 26984187 Clinical Trial.
The concept and diagnostic criteria of primary lateral sclerosis.
Wais V, Rosenbohm A, Petri S, Kollewe K, Hermann A, Storch A, Hanisch F, Zierz S, Nagel G, Kassubek J, Weydt P, Brettschneider J, Weishaupt JH, Ludolph AC, Dorst J. Wais V, et al. Among authors: weishaupt jh. Acta Neurol Scand. 2017 Sep;136(3):204-211. doi: 10.1111/ane.12713. Epub 2016 Nov 15. Acta Neurol Scand. 2017. PMID: 27858953
205 results