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Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG.
Ehteda A, Simon S, Franshaw L, Giorgi FM, Liu J, Joshi S, Rouaen JRC, Pang CNI, Pandher R, Mayoh C, Tang Y, Khan A, Ung C, Tolhurst O, Kankean A, Hayden E, Lehmann R, Shen S, Gopalakrishnan A, Trebilcock P, Gurova K, Gudkov AV, Norris MD, Haber M, Vittorio O, Tsoli M, Ziegler DS. Ehteda A, et al. Among authors: gudkov av. Cell Rep. 2021 Apr 13;35(2):108994. doi: 10.1016/j.celrep.2021.108994. Cell Rep. 2021. PMID: 33852836 Free article.
Involvement of MDR1 P-glycoprotein in multifactorial resistance to methotrexate.
Norris MD, De Graaf D, Haber M, Kavallaris M, Madafiglio J, Gilbert J, Kwan E, Stewart BW, Mechetner EB, Gudkov AV, Roninson IB. Norris MD, et al. Among authors: gudkov av. Int J Cancer. 1996 Mar 1;65(5):613-9. doi: 10.1002/(SICI)1097-0215(19960301)65:5<613::AID-IJC10>3.0.CO;2-8. Int J Cancer. 1996. PMID: 8598312 Free article.
Paradoxical role of apoptosis in tumor progression.
Gurova KV, Gudkov AV. Gurova KV, et al. Among authors: gudkov av. J Cell Biochem. 2003 Jan 1;88(1):128-37. doi: 10.1002/jcb.10382. J Cell Biochem. 2003. PMID: 12461782 Review.
p53 determines multidrug sensitivity of childhood neuroblastoma.
Xue C, Haber M, Flemming C, Marshall GM, Lock RB, MacKenzie KL, Gurova KV, Norris MD, Gudkov AV. Xue C, et al. Among authors: gudkov av. Cancer Res. 2007 Nov 1;67(21):10351-60. doi: 10.1158/0008-5472.CAN-06-4345. Cancer Res. 2007. PMID: 17974978
Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma.
Burkhart CA, Watt F, Murray J, Pajic M, Prokvolit A, Xue C, Flemming C, Smith J, Purmal A, Isachenko N, Komarov PG, Gurova KV, Sartorelli AC, Marshall GM, Norris MD, Gudkov AV, Haber M. Burkhart CA, et al. Among authors: gudkov av. Cancer Res. 2009 Aug 15;69(16):6573-80. doi: 10.1158/0008-5472.CAN-09-1075. Epub 2009 Aug 4. Cancer Res. 2009. PMID: 19654298 Free PMC article.
Anti-malaria drug blocks proteotoxic stress response: anti-cancer implications.
Neznanov N, Gorbachev AV, Neznanova L, Komarov AP, Gurova KV, Gasparian AV, Banerjee AK, Almasan A, Fairchild RL, Gudkov AV. Neznanov N, et al. Among authors: gudkov av. Cell Cycle. 2009 Dec;8(23):3960-70. doi: 10.4161/cc.8.23.10179. Epub 2009 Dec 25. Cell Cycle. 2009. PMID: 19901558 Free PMC article.
Inflammation and p53: A Tale of Two Stresses.
Gudkov AV, Gurova KV, Komarova EA. Gudkov AV, et al. Genes Cancer. 2011 Apr;2(4):503-16. doi: 10.1177/1947601911409747. Genes Cancer. 2011. PMID: 21779518 Free PMC article.
Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT.
Gasparian AV, Burkhart CA, Purmal AA, Brodsky L, Pal M, Saranadasa M, Bosykh DA, Commane M, Guryanova OA, Pal S, Safina A, Sviridov S, Koman IE, Veith J, Komar AA, Gudkov AV, Gurova KV. Gasparian AV, et al. Among authors: gudkov av. Sci Transl Med. 2011 Aug 10;3(95):95ra74. doi: 10.1126/scitranslmed.3002530. Sci Transl Med. 2011. PMID: 21832239 Free PMC article.
275 results