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Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease.
Mead S, Burnell M, Lowe J, Thompson A, Lukic A, Porter MC, Carswell C, Kaski D, Kenny J, Mok TH, Bjurstrom N, Franko E, Gorham M, Druyeh R, Wadsworth JD, Jaunmuktane Z, Brandner S, Hyare H, Rudge P, Walker AS, Collinge J. Mead S, et al. JAMA Neurol. 2016 Apr;73(4):447-55. doi: 10.1001/jamaneurol.2015.4885. JAMA Neurol. 2016. PMID: 26902324 Free PMC article.
Evaluating the causality of novel sequence variants in the prion protein gene by example.
Mok TH, Koriath C, Jaunmuktane Z, Campbell T, Joiner S, Wadsworth JDF, Hosszu LLP, Brandner S, Parvez A, Truelsen TC, Lund EL, Saha R, Collinge J, Mead S. Mok TH, et al. Neurobiol Aging. 2018 Nov;71:265.e1-265.e7. doi: 10.1016/j.neurobiolaging.2018.05.011. Epub 2018 May 15. Neurobiol Aging. 2018. PMID: 29861043 Free PMC article.
Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series.
Koriath C, Kenny J, Adamson G, Druyeh R, Taylor W, Beck J, Quinn L, Mok TH, Dimitriadis A, Norsworthy P, Bass N, Carter J, Walker Z, Kipps C, Coulthard E, Polke JM, Bernal-Quiros M, Denning N, Thomas R, Raybould R, Williams J, Mummery CJ, Wild EJ, Houlden H, Tabrizi SJ, Rossor MN, Hummerich H, Warren JD, Rowe JB, Rohrer JD, Schott JM, Fox NC, Collinge J, Mead S. Koriath C, et al. Among authors: mok th. Mol Psychiatry. 2020 Dec;25(12):3399-3412. doi: 10.1038/s41380-018-0224-0. Epub 2018 Oct 2. Mol Psychiatry. 2020. PMID: 30279455 Free PMC article.
Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseases.
Thompson AGB, Anastasiadis P, Druyeh R, Whitworth I, Nayak A, Nihat A, Mok TH, Rudge P, Wadsworth JDF, Rohrer J, Schott JM, Heslegrave A, Zetterberg H, Collinge J, Jackson GS, Mead S. Thompson AGB, et al. Mol Psychiatry. 2021 Oct;26(10):5955-5966. doi: 10.1038/s41380-021-01045-w. Epub 2021 Mar 5. Mol Psychiatry. 2021. PMID: 33674752 Free PMC article.
593 results