Darwish M - Search Results

1

High-throughput identification of conditional MHCI ligands and scaled-up production of conditional MHCI complexes.

Darwish M, Wichner S, Li J, Chang JC, Tam C, Franke Y, Li H, Chan P, Blanchette C. Darwish M, et al. Protein Sci. 2021 Jun;30(6):1169-1183. doi: 10.1002/pro.4082. Epub 2021 Apr 26. Protein Sci. 2021. PMID: 33840137 Free PMC article.

2

Total antibody quantification for MMAE-conjugated antibody-drug conjugates: impact of assay format and reagents.

Kozak KR, Tsai SP, Fourie-O'Donohue A, dela Cruz Chuh J, Roth L, Cook R, Chan E, Chan P, Darwish M, Ohri R, Raab H, Zhang C, Lin K, Wong WL. Kozak KR, et al. Among authors: darwish m. Bioconjug Chem. 2013 May 15;24(5):772-9. doi: 10.1021/bc300491k. Epub 2013 Apr 11. Bioconjug Chem. 2013. PMID: 23578050

3

Transposable element expression in tumors is associated with immune infiltration and increased antigenicity.

Kong Y, Rose CM, Cass AA, Williams AG, Darwish M, Lianoglou S, Haverty PM, Tong AJ, Blanchette C, Albert ML, Mellman I, Bourgon R, Greally J, Jhunjhunwala S, Chen-Harris H. Kong Y, et al. Among authors: darwish m. Nat Commun. 2019 Nov 19;10(1):5228. doi: 10.1038/s41467-019-13035-2. Nat Commun. 2019. PMID: 31745090 Free PMC article.

4

Nanolipoprotein Particles as a Delivery Platform for Fab Based Therapeutics.

Darwish M, Shatz W, Leonard B, Loyet K, Barrett K, Wong JL, Li H, Abraham R, Lin M, Franke Y, Tam C, Mortara K, Zilberleyb I, Blanchette C. Darwish M, et al. Bioconjug Chem. 2020 Aug 19;31(8):1995-2007. doi: 10.1021/acs.bioconjchem.0c00349. Epub 2020 Aug 5. Bioconjug Chem. 2020. PMID: 32701261

5

Sensitive and Quantitative Detection of MHC-I Displayed Neoepitopes Using a Semiautomated Workflow and TOMAHAQ Mass Spectrometry.

Pollock SB, Rose CM, Darwish M, Bouziat R, Delamarre L, Blanchette C, Lill JR. Pollock SB, et al. Among authors: darwish m. Mol Cell Proteomics. 2021;20:100108. doi: 10.1016/j.mcpro.2021.100108. Epub 2021 Jun 12. Mol Cell Proteomics. 2021. PMID: 34129938 Free PMC article.

6

Nanolipoprotein particles for co-delivery of cystine-knot peptides and Fab-based therapeutics.

Darwish M, Gao X, Shatz W, Li H, Lin M, Franke Y, Tam C, Mortara K, Zilberleyb I, Hannoush RN, Blanchette C. Darwish M, et al. Nanoscale Adv. 2021 Jun 1;3(13):3929-3941. doi: 10.1039/d1na00218j. eCollection 2021 Jun 30. Nanoscale Adv. 2021. PMID: 36133017 Free PMC article.

7

Case report: A persistently expanded T cell response in an exceptional responder to radiation and atezolizumab for metastatic non-small cell lung cancer.

Coffey DG, Xu Y, Towlerton AMH, Kowanetz M, Hegde P, Darwish M, Yadav M, Blanchette C, Ruppert SM, Bertino S, Xu Q, Ferretti A, Weinheimer A, Hellmann M, Qin A, Thomas D, Warren EH, Ramnath N. Coffey DG, et al. Among authors: darwish m. Front Immunol. 2022 Sep 9;13:961105. doi: 10.3389/fimmu.2022.961105. eCollection 2022. Front Immunol. 2022. PMID: 36159875 Free PMC article.

8

High-Throughput, Quantitative Analysis of Peptide-Exchanged MHCI Complexes by Native Mass Spectrometry.

Schachner LF, Phung W, Han G, Darwish M, Bell A, Mellors JS, Srzentic K, Huguet R, Blanchette C, Sandoval W. Schachner LF, et al. Among authors: darwish m. Anal Chem. 2022 Oct 25;94(42):14593-14602. doi: 10.1021/acs.analchem.2c02423. Epub 2022 Sep 30. Anal Chem. 2022. PMID: 36179215 Free PMC article.

9

Systematic discovery of neoepitope-HLA pairs for neoantigens shared among patients and tumor types.

Gurung HR, Heidersbach AJ, Darwish M, Chan PPF, Li J, Beresini M, Zill OA, Wallace A, Tong AJ, Hascall D, Torres E, Chang A, Lou K', Abdolazimi Y, Hammer C, Xavier-Magalhães A, Marcu A, Vaidya S, Le DD, Akhmetzyanova I, Oh SA, Moore AJ, Uche UN, Laur MB, Notturno RJ, Ebert PJR, Blanchette C, Haley B, Rose CM. Gurung HR, et al. Among authors: darwish m. Nat Biotechnol. 2023 Oct 19. doi: 10.1038/s41587-023-01945-y. Online ahead of print. Nat Biotechnol. 2023. PMID: 37857725

10

FRET Reagent Reveals the Intracellular Processing of Peptide-Linked Antibody-Drug Conjugates.

Lee BC, Chalouni C, Doll S, Nalle SC, Darwish M, Tsai SP, Kozak KR, Del-Rosario G, Yu SF, Erickson H, Vandlen R. Lee BC, et al. Among authors: darwish m. Bioconjug Chem. 2018 Jul 18;29(7):2468-2477. doi: 10.1021/acs.bioconjchem.8b00362. Epub 2018 Jun 13. Bioconjug Chem. 2018. PMID: 29856915

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