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The intracellular environment affects protein-protein interactions.
Speer SL, Zheng W, Jiang X, Chu IT, Guseman AJ, Liu M, Pielak GJ, Li C. Speer SL, et al. Among authors: jiang x. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2019918118. doi: 10.1073/pnas.2019918118. Proc Natl Acad Sci U S A. 2021. PMID: 33836588 Free PMC article.
Membrane-mediated disorder-to-order transition of SNAP25 flexible linker facilitates its interaction with syntaxin-1 and SNARE-complex assembly.
Jiang X, Zhang Z, Cheng K, Wu Q, Jiang L, Pielak GJ, Liu M, Li C. Jiang X, et al. Among authors: jiang l. FASEB J. 2019 Jul;33(7):7985-7994. doi: 10.1096/fj.201802796R. Epub 2019 Mar 27. FASEB J. 2019. PMID: 30916996
Our work elucidates the role of the flexible loop and the membrane environment in SNARE-complex assembly at the residue level, which helps to understand membrane fusion, a fundamental transport and communication process in cells.-Jiang, X., Zhang, Z., Cheng, K., Wu, …
Our work elucidates the role of the flexible loop and the membrane environment in SNARE-complex assembly at the residue level, which helps t …
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