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miR-132/212 Impairs Cardiomyocytes Contractility in the Failing Heart by Suppressing SERCA2a.
Lei Z, Wahlquist C, El Azzouzi H, Deddens JC, Kuster D, van Mil A, Rojas-Munoz A, Huibers MM, Mercola M, de Weger R, Van der Velden J, Xiao J, Doevendans PA, Sluijter JPG. Lei Z, et al. Among authors: de weger r. Front Cardiovasc Med. 2021 Mar 19;8:592362. doi: 10.3389/fcvm.2021.592362. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 33816571 Free PMC article.
Increased circulating IgG levels, myocardial immune cells and IgG deposits support a role for an immune response in pre- and end-stage heart failure.
van den Hoogen P, de Jager SCA, Huibers MMH, Schoneveld AH, Puspitasari YM, Valstar GB, Oerlemans MIFJ, de Weger RA, Doevendans PA, den Ruijter HM, Laman JD, Vink A, Sluijter JPG. van den Hoogen P, et al. Among authors: de weger ra. J Cell Mol Med. 2019 Nov;23(11):7505-7516. doi: 10.1111/jcmm.14619. Epub 2019 Sep 26. J Cell Mol Med. 2019. PMID: 31557411 Free PMC article.
H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts.
Pei J, Harakalova M, Treibel TA, Lumbers RT, Boukens BJ, Efimov IR, van Dinter JT, González A, López B, El Azzouzi H, van den Dungen N, van Dijk CGM, Krebber MM, den Ruijter HM, Pasterkamp G, Duncker DJ, Nieuwenhuis EES, de Weger R, Huibers MM, Vink A, Moore JH, Moon JC, Verhaar MC, Kararigas G, Mokry M, Asselbergs FW, Cheng C. Pei J, et al. Among authors: de weger r. Clin Epigenetics. 2020 Jul 14;12(1):106. doi: 10.1186/s13148-020-00895-5. Clin Epigenetics. 2020. PMID: 32664951 Free PMC article.
MicroRNA Expression in Myocardial Tissue and Plasma of Patients with End-Stage Heart Failure during LVAD Support: Comparison of Continuous and Pulsatile Devices.
Lok SI, de Jonge N, van Kuik J, van Geffen AJ, Huibers MM, van der Weide P, Siera E, Winkens B, Doevendans PA, de Weger RA, da Costa Martins PA. Lok SI, et al. PLoS One. 2015 Oct 2;10(10):e0136404. doi: 10.1371/journal.pone.0136404. eCollection 2015. PLoS One. 2015. PMID: 26430739 Free PMC article.
Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure.
Raso A, Dirkx E, Philippen LE, Fernandez-Celis A, De Majo F, Sampaio-Pinto V, Sansonetti M, Juni R, El Azzouzi H, Calore M, Bitsch N, Olieslagers S, Oerlemans MIFJ, Huibers MM, de Weger RA, Reckman YJ, Pinto YM, Zentilin L, Zacchigna S, Giacca M, da Costa Martins PA, López-Andrés N, De Windt LJ. Raso A, et al. Among authors: de windt lj, de majo f, de weger ra. Mol Ther. 2019 Mar 6;27(3):584-599. doi: 10.1016/j.ymthe.2018.11.011. Epub 2018 Nov 17. Mol Ther. 2019. PMID: 30559069 Free PMC article.
253 results