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A cytoskeletal function for PBRM1 reading methylated microtubules.
Karki M, Jangid RK, Anish R, Seervai RNH, Bertocchio JP, Hotta T, Msaouel P, Jung SY, Grimm SL, Coarfa C, Weissman BE, Ohi R, Verhey KJ, Hodges HC, Burggren W, Dere R, Park IY, Prasad BVV, Rathmell WK, Walker CL, Tripathi DN. Karki M, et al. Among authors: park iy. Sci Adv. 2021 Apr 2;7(14):eabf2866. doi: 10.1126/sciadv.abf2866. Print 2021 Apr. Sci Adv. 2021. PMID: 33811077 Free PMC article.
Dual Chromatin and Cytoskeletal Remodeling by SETD2.
Park IY, Powell RT, Tripathi DN, Dere R, Ho TH, Blasius TL, Chiang YC, Davis IJ, Fahey CC, Hacker KE, Verhey KJ, Bedford MT, Jonasch E, Rathmell WK, Walker CL. Park IY, et al. Cell. 2016 Aug 11;166(4):950-962. doi: 10.1016/j.cell.2016.07.005. Cell. 2016. PMID: 27518565 Free PMC article.
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
Seervai RNH, Jangid RK, Karki M, Tripathi DN, Jung SY, Kearns SE, Verhey KJ, Cianfrocco MA, Millis BA, Tyska MJ, Mason FM, Rathmell WK, Park IY, Dere R, Walker CL. Seervai RNH, et al. Among authors: park iy. Sci Adv. 2020 Oct 2;6(40):eabb7854. doi: 10.1126/sciadv.abb7854. Print 2020 Oct. Sci Adv. 2020. PMID: 33008892 Free PMC article.
SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma.
Chiang YC, Park IY, Terzo EA, Tripathi DN, Mason FM, Fahey CC, Karki M, Shuster CB, Sohn BH, Chowdhury P, Powell RT, Ohi R, Tsai YS, de Cubas AA, Khan A, Davis IJ, Strahl BD, Parker JS, Dere R, Walker CL, Rathmell WK. Chiang YC, et al. Among authors: park iy. Cancer Res. 2018 Jun 15;78(12):3135-3146. doi: 10.1158/0008-5472.CAN-17-3460. Epub 2018 May 3. Cancer Res. 2018. PMID: 29724720 Free PMC article.
Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice.
Koenning M, Wang X, Karki M, Jangid RK, Kearns S, Tripathi DN, Cianfrocco M, Verhey KJ, Jung SY, Coarfa C, Ward CS, Kalish BT, Grimm SL, Rathmell WK, Mostany R, Dere R, Rasband MN, Walker CL, Park IY. Koenning M, et al. Among authors: park iy. Brain. 2021 Sep 4;144(8):2527-2540. doi: 10.1093/brain/awab200. Brain. 2021. PMID: 34014281 Free PMC article.
Molecular determinants for α-tubulin methylation by SETD2.
Kearns S, Mason FM, Rathmell WK, Park IY, Walker C, Verhey KJ, Cianfrocco MA. Kearns S, et al. Among authors: park iy. J Biol Chem. 2021 Jul;297(1):100898. doi: 10.1016/j.jbc.2021.100898. Epub 2021 Jun 19. J Biol Chem. 2021. PMID: 34157286 Free PMC article.
HNF1B Loss Exacerbates the Development of Chromophobe Renal Cell Carcinomas.
Sun M, Tong P, Kong W, Dong B, Huang Y, Park IY, Zhou L, Liu XD, Ding Z, Zhang X, Bai S, German P, Powell R, Wang Q, Tong X, Tannir NM, Matin SF, Rathmell WK, Fuller GN, McCutcheon IE, Walker CL, Wang J, Jonasch E. Sun M, et al. Among authors: park iy. Cancer Res. 2017 Oct 1;77(19):5313-5326. doi: 10.1158/0008-5472.CAN-17-0986. Epub 2017 Aug 14. Cancer Res. 2017. PMID: 28807937 Free PMC article.
High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma.
Ho TH, Park IY, Zhao H, Tong P, Champion MD, Yan H, Monzon FA, Hoang A, Tamboli P, Parker AS, Joseph RW, Qiao W, Dykema K, Tannir NM, Castle EP, Nunez-Nateras R, Teh BT, Wang J, Walker CL, Hung MC, Jonasch E. Ho TH, et al. Among authors: park iy. Oncogene. 2016 Mar 24;35(12):1565-74. doi: 10.1038/onc.2015.221. Epub 2015 Jun 15. Oncogene. 2016. PMID: 26073078 Free PMC article.
314 results