Martínez A - Search Results

1

Molecular Alterations in Sporadic and SOD1-ALS Immortalized Lymphocytes: Towards a Personalized Therapy.

Lastres-Becker I, Porras G, Arribas-Blázquez M, Maestro I, Borrego-Hernández D, Boya P, Cerdán S, García-Redondo A, Martínez A, Martin-Requero Á. Lastres-Becker I, et al. Among authors: martinez a. Int J Mol Sci. 2021 Mar 16;22(6):3007. doi: 10.3390/ijms22063007. Int J Mol Sci. 2021. PMID: 33809456 Free PMC article.

2

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

Alquezar C, Salado IG, de la Encarnación A, Pérez DI, Moreno F, Gil C, de Munain AL, Martínez A, Martín-Requero Á. Alquezar C, et al. Among authors: martinez a. Mol Neurodegener. 2016 Apr 30;11(1):36. doi: 10.1186/s13024-016-0102-7. Mol Neurodegener. 2016. PMID: 27138926 Free PMC article.

3

Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients.

Posa D, Martínez-González L, Bartolomé F, Nagaraj S, Porras G, Martínez A, Martín-Requero Á. Posa D, et al. Among authors: martinez gonzalez l, martinez a. Mol Neurobiol. 2019 Apr;56(4):2424-2432. doi: 10.1007/s12035-018-1249-8. Epub 2018 Jul 20. Mol Neurobiol. 2019. PMID: 30030753

4

TDP-43: A Key Therapeutic Target beyond Amyotrophic Lateral Sclerosis.

Palomo V, Tosat-Bitrian C, Nozal V, Nagaraj S, Martin-Requero A, Martinez A. Palomo V, et al. Among authors: martinez a. ACS Chem Neurosci. 2019 Mar 20;10(3):1183-1196. doi: 10.1021/acschemneuro.9b00026. Epub 2019 Mar 4. ACS Chem Neurosci. 2019. PMID: 30785719 Free article. Review.

5

Serum- and glucocorticoid-induced kinase 1, a new therapeutic target for autophagy modulation in chronic diseases.

Maestro I, Boya P, Martinez A. Maestro I, et al. Among authors: martinez a. Expert Opin Ther Targets. 2020 Mar;24(3):231-243. doi: 10.1080/14728222.2020.1730328. Epub 2020 Feb 18. Expert Opin Ther Targets. 2020. PMID: 32067528 Review.

6

Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment.

Martínez-González L, Rodríguez-Cueto C, Cabezudo D, Bartolomé F, Andrés-Benito P, Ferrer I, Gil C, Martín-Requero Á, Fernández-Ruiz J, Martínez A, de Lago E. Martínez-González L, et al. Among authors: martinez a. Sci Rep. 2020 Mar 10;10(1):4449. doi: 10.1038/s41598-020-61265-y. Sci Rep. 2020. PMID: 32157143 Free PMC article.

7

COVID-19: Drug Targets and Potential Treatments.

Gil C, Ginex T, Maestro I, Nozal V, Barrado-Gil L, Cuesta-Geijo MÁ, Urquiza J, Ramírez D, Alonso C, Campillo NE, Martinez A. Gil C, et al. Among authors: martinez a. J Med Chem. 2020 Nov 12;63(21):12359-12386. doi: 10.1021/acs.jmedchem.0c00606. Epub 2020 Jun 26. J Med Chem. 2020. PMID: 32511912 Free article. Review.

8

Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Vaca G, Martinez-Gonzalez L, Fernandez A, Rojas-Prats E, Porras G, Cuevas EP, Gil C, Martinez A, Martin-Requero Á. Vaca G, et al. Among authors: martinez gonzalez l, martinez a. J Neurochem. 2021 Feb;156(3):379-390. doi: 10.1111/jnc.15118. Epub 2020 Jul 17. J Neurochem. 2021. PMID: 32628315 Free article.

9

Cognitive enhancement, TAU phosphorylation reduction, and neuronal protection by the treatment of an LRRK2 inhibitor in a tauopathy mouse model.

Castro-Sánchez S, Zaldivar-Diez J, Luengo E, López MG, Gil C, Martínez A, Lastres-Becker I. Castro-Sánchez S, et al. Among authors: martinez a. Neurobiol Aging. 2020 Dec;96:148-154. doi: 10.1016/j.neurobiolaging.2020.09.006. Epub 2020 Sep 8. Neurobiol Aging. 2020. PMID: 33007689 Free article.

10

Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis.

Rojas-Prats E, Martinez-Gonzalez L, Gonzalo-Consuegra C, Liachko NF, Perez C, Ramírez D, Kraemer BC, Martin-Requero Á, Perez DI, Gil C, de Lago E, Martinez A. Rojas-Prats E, et al. Among authors: martinez gonzalez l, martinez a. Eur J Med Chem. 2021 Jan 15;210:112968. doi: 10.1016/j.ejmech.2020.112968. Epub 2020 Oct 28. Eur J Med Chem. 2021. PMID: 33139113

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