Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation.
Pavlaki N, Froese A, Li W, De Jong KA, Geertz B, Subramanian H, Mohagaonkar S, Luo X, Schubert M, Wiegmann R, Margaria JP, Ghigo A, Kämmerer S, Hirsch E, El-Armouche A, Guan K, Nikolaev VO.
Pavlaki N, et al. Among authors: de jong ka.
Cardiovasc Res. 2024 May 22:cvae094. doi: 10.1093/cvr/cvae094. Online ahead of print.
Cardiovasc Res. 2024.
PMID: 38776406