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Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3Kδ Immunomodulators.
Methot JL, Zhou H, McGowan MA, Anthony NJ, Christopher M, Garcia Y, Achab A, Lipford K, Trotter BW, Altman MD, Fradera X, Lesburg CA, Li C, Alves S, Chappell CP, Jain R, Mangado R, Pinheiro E, Williams SMG, Goldenblatt P, Hill A, Shaffer L, Chen D, Tong V, McLeod RL, Lee HH, Yu H, Shah S, Katz JD. Methot JL, et al. Among authors: chappell cp. J Med Chem. 2021 Apr 22;64(8):5137-5156. doi: 10.1021/acs.jmedchem.1c00237. Epub 2021 Apr 2. J Med Chem. 2021. PMID: 33797901
B-cell selection and the development of autoantibodies.
Giltiay NV, Chappell CP, Clark EA. Giltiay NV, et al. Among authors: chappell cp. Arthritis Res Ther. 2012;14 Suppl 4(Suppl 4):S1. doi: 10.1186/ar3918. Epub 2012 Nov 2. Arthritis Res Ther. 2012. PMID: 23281837 Free PMC article. Review.
STALing B cell responses with CD22.
Chappell CP, Clark EA. Chappell CP, et al. J Clin Invest. 2013 Jul;123(7):2778-80. doi: 10.1172/JCI69670. Epub 2013 Jun 3. J Clin Invest. 2013. PMID: 23722900 Free PMC article.
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