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TAP dysfunction in dendritic cells enables noncanonical cross-presentation for T cell priming.
Nat Immunol. 2021 Apr;22(4):497-509. doi: 10.1038/s41590-021-00903-7. Epub 2021 Mar 31.
Nat Immunol. 2021.
PMID: 33790474
Free PMC article.
An updated view of the intracellular mechanisms regulating cross-presentation.
Nair-Gupta P, Blander JM.
Nair-Gupta P, et al.
Front Immunol. 2013 Nov 22;4:401. doi: 10.3389/fimmu.2013.00401.
Front Immunol. 2013.
PMID: 24319447
Free PMC article.
Review.
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TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation.
Nair-Gupta P, Baccarini A, Tung N, Seyffer F, Florey O, Huang Y, Banerjee M, Overholtzer M, Roche PA, Tampé R, Brown BD, Amsen D, Whiteheart SW, Blander JM.
Nair-Gupta P, et al.
Cell. 2014 Jul 31;158(3):506-21. doi: 10.1016/j.cell.2014.04.054.
Cell. 2014.
PMID: 25083866
Free PMC article.
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A novel C2 domain binding CD33xCD3 bispecific antibody with potent T-cell redirection activity against acute myeloid leukemia.
Nair-Gupta P, Diem M, Reeves D, Wang W, Schulingkamp R, Sproesser K, Mattson B, Heidrich B, Mendonça M, Joseph J, Sendecki J, Foulk B, Chu G, Fink D, Jiao Q, Wu SJ, Packman K, Elsayed Y, Attar R, Gaudet F.
Nair-Gupta P, et al.
Blood Adv. 2020 Mar 10;4(5):906-919. doi: 10.1182/bloodadvances.2019001188.
Blood Adv. 2020.
PMID: 32150609
Free PMC article.
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Blockade of VLA4 sensitizes leukemic and myeloma tumor cells to CD3 redirection in the bone marrow microenvironment.
Nair-Gupta P, Rudnick SI, Luistro L, Smith M, McDaid R, Li Y, Pillarisetti K, Joseph J, Heidrich B, Packman K, Attar R, Gaudet F.
Nair-Gupta P, et al.
Blood Cancer J. 2020 Jun 1;10(6):65. doi: 10.1038/s41408-020-0331-4.
Blood Cancer J. 2020.
PMID: 32483120
Free PMC article.
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