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TAP dysfunction in dendritic cells enables noncanonical cross-presentation for T cell priming.
Barbet G, Nair-Gupta P, Schotsaert M, Yeung ST, Moretti J, Seyffer F, Metreveli G, Gardner T, Choi A, Tortorella D, Tampé R, Khanna KM, García-Sastre A, Blander JM. Barbet G, et al. Among authors: nair gupta p. Nat Immunol. 2021 Apr;22(4):497-509. doi: 10.1038/s41590-021-00903-7. Epub 2021 Mar 31. Nat Immunol. 2021. PMID: 33790474 Free PMC article.
A novel C2 domain binding CD33xCD3 bispecific antibody with potent T-cell redirection activity against acute myeloid leukemia.
Nair-Gupta P, Diem M, Reeves D, Wang W, Schulingkamp R, Sproesser K, Mattson B, Heidrich B, Mendonça M, Joseph J, Sendecki J, Foulk B, Chu G, Fink D, Jiao Q, Wu SJ, Packman K, Elsayed Y, Attar R, Gaudet F. Nair-Gupta P, et al. Blood Adv. 2020 Mar 10;4(5):906-919. doi: 10.1182/bloodadvances.2019001188. Blood Adv. 2020. PMID: 32150609 Free PMC article.