Tarazi H - Search Results

1

Camel whey protein hydrolysates induced G2/M cellcycle arrest in human colorectal carcinoma.

Murali C, Mudgil P, Gan CY, Tarazi H, El-Awady R, Abdalla Y, Amin A, Maqsood S. Murali C, et al. Among authors: tarazi h. Sci Rep. 2021 Mar 29;11(1):7062. doi: 10.1038/s41598-021-86391-z. Sci Rep. 2021. PMID: 33782460 Free PMC article.

2

In-silico screening for DNA-dependent protein kinase (DNA-PK) inhibitors: Combined homology modeling, docking, molecular dynamic study followed by biological investigation.

Tarazi H, Saleh E, El-Awady R. Tarazi H, et al. Biomed Pharmacother. 2016 Oct;83:693-703. doi: 10.1016/j.biopha.2016.07.044. Epub 2016 Jul 28. Biomed Pharmacother. 2016. PMID: 27470570

3

Post-Ugi Cascade Transformations for Accessing Diverse Chromenopyrrole Collections.

Srinivasulu V, Sieburth SM, El-Awady R, Kariem NM, Tarazi H, O'Connor MJ, Al-Tel TH. Srinivasulu V, et al. Among authors: tarazi h. Org Lett. 2018 Feb 2;20(3):836-839. doi: 10.1021/acs.orglett.7b03986. Epub 2018 Jan 12. Org Lett. 2018. PMID: 29327591

4

Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types.

Vazhappilly CG, Saleh E, Ramadan W, Menon V, Al-Azawi AM, Tarazi H, Abdu-Allah H, El-Shorbagi AN, El-Awady R. Vazhappilly CG, et al. Among authors: tarazi h. Invest New Drugs. 2019 Apr;37(2):252-261. doi: 10.1007/s10637-018-0626-5. Epub 2018 Jun 27. Invest New Drugs. 2019. PMID: 29947013

5

Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells.

Al-Hrout A, Chaiboonchoe A, Khraiwesh B, Murali C, Baig B, El-Awady R, Tarazi H, Alzahmi A, Nelson DR, Greish YE, Ramadan W, Salehi-Ashtiani K, Amin A. Al-Hrout A, et al. Among authors: tarazi h. Sci Rep. 2018 Nov 16;8(1):16951. doi: 10.1038/s41598-018-34855-0. Sci Rep. 2018. PMID: 30446676 Free PMC article.

6

Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.

Abdu-Allah HHM, Abdelmoez AAB, Tarazi H, El-Shorbagi AA, El-Awady R. Abdu-Allah HHM, et al. Among authors: tarazi h. Bioorg Chem. 2020 Jan;94:103378. doi: 10.1016/j.bioorg.2019.103378. Epub 2019 Oct 24. Bioorg Chem. 2020. PMID: 31677858

7

Design and synthesis of new quinoline derivatives as selective C-RAF kinase inhibitors with potent anticancer activity.

Zaraei SO, Al-Ach NN, Anbar HS, El-Gamal R, Tarazi H, Tokatly RT, Kalla RR, Munther MA, Wahba MM, Alshihabi AM, Shehata MK, Sbenati RM, Shahin AI, El-Awady R, Al-Tel TH, El-Gamal MI. Zaraei SO, et al. Among authors: tarazi h. Eur J Med Chem. 2022 Aug 5;238:114434. doi: 10.1016/j.ejmech.2022.114434. Epub 2022 May 5. Eur J Med Chem. 2022. PMID: 35551038

8

Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives.

Ramadan WS, Saber-Ayad MM, Saleh E, Abdu-Allah HHM, El-Shorbagi AA, Menon V, Tarazi H, Semreen MH, Soares NC, Hafezi S, Venkatakhalam T, Ahmed S, Kanie O, Hamoudi R, El-Awady R. Ramadan WS, et al. Among authors: tarazi h. iScience. 2023 Dec 9;27(1):108659. doi: 10.1016/j.isci.2023.108659. eCollection 2024 Jan 19. iScience. 2023. PMID: 38235331 Free PMC article.

9

Design, synthesis and biological evaluation of new pyrrolidine carboxamide analogues as potential chemotherapeutic agents for hepatocellular carcinoma.

Omar HA, Zaher DM, Srinivasulu V, Hersi F, Tarazi H, Al-Tel TH. Omar HA, et al. Among authors: tarazi h. Eur J Med Chem. 2017 Oct 20;139:804-814. doi: 10.1016/j.ejmech.2017.08.054. Epub 2017 Aug 26. Eur J Med Chem. 2017. PMID: 28865276

10

Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative agents against hepatocellular carcinoma cells.

Sbenati RM, Zaraei SO, El-Gamal MI, Anbar HS, Tarazi H, Zoghbor MM, Mohamood NA, Khakpour MM, Zaher DM, Omar HA, Alach NN, Shehata MK, El-Gamal R. Sbenati RM, et al. Among authors: tarazi h. Eur J Med Chem. 2021 Jan 15;210:113081. doi: 10.1016/j.ejmech.2020.113081. Epub 2020 Dec 4. Eur J Med Chem. 2021. PMID: 33310290

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