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Dibenzyl trisulfide binds to and competitively inhibits the cytochrome P450 1A1 active site without impacting the expression of the aryl hydrocarbon receptor.
Wauchope S, Roy MA, Irvine W, Morrison I, Brantley E, Gossell-Williams M, Timme-Laragy AR, Delgoda R. Wauchope S, et al. Among authors: brantley e. Toxicol Appl Pharmacol. 2021 May 15;419:115502. doi: 10.1016/j.taap.2021.115502. Epub 2021 Mar 24. Toxicol Appl Pharmacol. 2021. PMID: 33774063 Free PMC article.
Glaucarubulone glucoside from Castela macrophylla suppresses MCF-7 breast cancer cell growth and attenuates benzo[a]pyrene-mediated CYP1A gene induction.
Badal SAM, Asuncion Valenzuela MM, Zylstra D, Huang G, Vendantam P, Francis S, Quitugua A, Amis LH, Davis W, Tzeng TJ, Jacobs H, Gangemi DJ, Raner G, Rowland L, Wooten J, Campbell P, Brantley E, Delgoda R. Badal SAM, et al. Among authors: brantley e. J Appl Toxicol. 2017 Jul;37(7):873-883. doi: 10.1002/jat.3436. Epub 2017 Jan 31. J Appl Toxicol. 2017. PMID: 28138972 Free PMC article.
Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells.
McLean LS, Watkins CN, Campbell P, Zylstra D, Rowland L, Amis LH, Scott L, Babb CE, Livingston WJ, Darwanto A, Davis WL Jr, Senthil M, Sowers LC, Brantley E. McLean LS, et al. Among authors: brantley e. Chem Res Toxicol. 2015 May 18;28(5):855-71. doi: 10.1021/tx500485v. Epub 2015 Apr 1. Chem Res Toxicol. 2015. PMID: 25781201 Free PMC article.
AhR ligand aminoflavone suppresses α6-integrin-Src-Akt signaling to attenuate tamoxifen resistance in breast cancer cells.
Campbell PS, Mavingire N, Khan S, Rowland LK, Wooten JV, Opoku-Agyeman A, Guevara A, Soto U, Cavalli F, Loaiza-Pérez AI, Nagaraj G, Denham LJ, Adeoye O, Jenkins BD, Davis MB, Schiff R, Brantley EJ. Campbell PS, et al. J Cell Physiol. 2018 Jan;234(1):108-121. doi: 10.1002/jcp.27013. Epub 2018 Aug 4. J Cell Physiol. 2018. PMID: 30076704 Free PMC article.
53 results