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Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength.
Martin PT, Zygmunt DA, Ashbrook A, Hamilton S, Packer D, Birch SM, Bettis AK, Balog-Alvarez CJ, Guo LJ, Nghiem PP, Kornegay JN. Martin PT, et al. Among authors: ashbrook a. PLoS One. 2021 Mar 26;16(3):e0248721. doi: 10.1371/journal.pone.0248721. eCollection 2021. PLoS One. 2021. PMID: 33770101 Free PMC article.
Serum Antibodies to N-Glycolylneuraminic Acid Are Elevated in Duchenne Muscular Dystrophy and Correlate with Increased Disease Pathology in Cmah-/-mdx Mice.
Martin PT, Kawanishi K, Ashbrook A, Golden B, Samraj A, Crowe KE, Zygmunt DA, Okerblom J, Yu H, Maki A, Diaz S, Chen X, Janssen PML, Varki A. Martin PT, et al. Among authors: ashbrook a. Am J Pathol. 2021 Aug;191(8):1474-1486. doi: 10.1016/j.ajpath.2021.04.015. Am J Pathol. 2021. PMID: 34294193 Free PMC article.
Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.
Lercher A, Cheong JG, Jiang C, Hoffmann HH, Ashbrook AW, Yin YS, Quirk C, DeGrace EJ, Chiriboga L, Rosenberg BR, Josefowicz SZ, Rice CM. Lercher A, et al. Among authors: ashbrook aw. bioRxiv [Preprint]. 2023 Nov 27:2023.11.24.568354. doi: 10.1101/2023.11.24.568354. bioRxiv. 2023. PMID: 38076887 Free PMC article. Preprint.
Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice.
Kabbani M, Michailidis E, Steensels S, Fulmer CG, Luna JM, Le Pen J, Tardelli M, Razooky B, Ricardo-Lax I, Zou C, Zeck B, Stenzel AF, Quirk C, Foquet L, Ashbrook AW, Schneider WM, Belkaya S, Lalazar G, Liang Y, Pittman M, Devisscher L, Suemizu H, Theise ND, Chiriboga L, Cohen DE, Copenhaver R, Grompe M, Meuleman P, Ersoy BA, Rice CM, de Jong YP. Kabbani M, et al. Among authors: ashbrook aw. Cell Rep. 2022 Sep 13;40(11):111321. doi: 10.1016/j.celrep.2022.111321. Cell Rep. 2022. PMID: 36103835 Free article.
36 results