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Krabbe disease: New hope for an old disease.
Bradbury AM, Bongarzone ER, Sands MS. Bradbury AM, et al. Among authors: bongarzone er. Neurosci Lett. 2021 May 1;752:135841. doi: 10.1016/j.neulet.2021.135841. Epub 2021 Mar 22. Neurosci Lett. 2021. PMID: 33766733 Free PMC article. Review.
Axonopathy is a compounding factor in the pathogenesis of Krabbe disease.
Castelvetri LC, Givogri MI, Zhu H, Smith B, Lopez-Rosas A, Qiu X, van Breemen R, Bongarzone ER. Castelvetri LC, et al. Among authors: bongarzone er. Acta Neuropathol. 2011 Jul;122(1):35-48. doi: 10.1007/s00401-011-0814-2. Epub 2011 Mar 4. Acta Neuropathol. 2011. PMID: 21373782 Free PMC article.
The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors.
Cantuti Castelvetri L, Givogri MI, Hebert A, Smith B, Song Y, Kaminska A, Lopez-Rosas A, Morfini G, Pigino G, Sands M, Brady ST, Bongarzone ER. Cantuti Castelvetri L, et al. Among authors: bongarzone er. J Neurosci. 2013 Jun 12;33(24):10048-56. doi: 10.1523/JNEUROSCI.0217-13.2013. J Neurosci. 2013. PMID: 23761900 Free PMC article.
101 results