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Page 1
The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity.
Szappanos D, Tschismarov R, Perlot T, Westermayer S, Fischer K, Platanitis E, Kallinger F, Novatchkova M, Lassnig C, Müller M, Sexl V, Bennett KL, Foong-Sobis M, Penninger JM, Decker T. Szappanos D, et al. Among authors: tschismarov r. PLoS Pathog. 2018 Nov 26;14(11):e1007397. doi: 10.1371/journal.ppat.1007397. eCollection 2018 Nov. PLoS Pathog. 2018. PMID: 30475900 Free PMC article.
Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation.
Preglej T, Hamminger P, Luu M, Bulat T, Andersen L, Göschl L, Stolz V, Rica R, Sandner L, Waltenberger D, Tschismarov R, Faux T, Boenke T, Laiho A, Elo LL, Sakaguchi S, Steiner G, Decker T, Bohle B, Visekruna A, Bock C, Strobl B, Seiser C, Boucheron N, Ellmeier W. Preglej T, et al. Among authors: tschismarov r. JCI Insight. 2020 Feb 27;5(4):e133393. doi: 10.1172/jci.insight.133393. JCI Insight. 2020. PMID: 32102981 Free PMC article.
Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signalling.
Nandakumar R, Tschismarov R, Meissner F, Prabakaran T, Krissanaprasit A, Farahani E, Zhang BC, Assil S, Martin A, Bertrams W, Holm CK, Ablasser A, Klause T, Thomsen MK, Schmeck B, Howard KA, Henry T, Gothelf KV, Decker T, Paludan SR. Nandakumar R, et al. Among authors: tschismarov r. Nat Microbiol. 2019 Apr;4(4):701-713. doi: 10.1038/s41564-019-0367-z. Epub 2019 Feb 25. Nat Microbiol. 2019. PMID: 30804548 Free PMC article.
HDAC1 controls CD8+ T cell homeostasis and antiviral response.
Tschismarov R, Firner S, Gil-Cruz C, Göschl L, Boucheron N, Steiner G, Matthias P, Seiser C, Ludewig B, Ellmeier W. Tschismarov R, et al. PLoS One. 2014 Oct 21;9(10):e110576. doi: 10.1371/journal.pone.0110576. eCollection 2014. PLoS One. 2014. PMID: 25333902 Free PMC article.
CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.
Boucheron N, Tschismarov R, Goeschl L, Moser MA, Lagger S, Sakaguchi S, Winter M, Lenz F, Vitko D, Breitwieser FP, Müller L, Hassan H, Bennett KL, Colinge J, Schreiner W, Egawa T, Taniuchi I, Matthias P, Seiser C, Ellmeier W. Boucheron N, et al. Among authors: tschismarov r. Nat Immunol. 2014 May;15(5):439-448. doi: 10.1038/ni.2864. Epub 2014 Mar 30. Nat Immunol. 2014. PMID: 24681565 Free PMC article.
Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production.
Grausenburger R, Bilic I, Boucheron N, Zupkovitz G, El-Housseiny L, Tschismarov R, Zhang Y, Rembold M, Gaisberger M, Hartl A, Epstein MM, Matthias P, Seiser C, Ellmeier W. Grausenburger R, et al. Among authors: tschismarov r. J Immunol. 2010 Sep 15;185(6):3489-97. doi: 10.4049/jimmunol.0903610. Epub 2010 Aug 11. J Immunol. 2010. PMID: 20702731 Free PMC article.
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