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The organometallic ferrocene exhibits amplified anti-tumor activity by targeted delivery via highly selective ligands to αvβ3, αvβ6, or α5β1 integrins.
Ludwig BS, Tomassi S, Di Maro S, Di Leva FS, Benge A, Reichart F, Nieberler M, Kühn FE, Kessler H, Marinelli L, Reuning U, Kossatz S. Ludwig BS, et al. Among authors: reichart f. Biomaterials. 2021 Apr;271:120754. doi: 10.1016/j.biomaterials.2021.120754. Epub 2021 Mar 12. Biomaterials. 2021. PMID: 33756215
Fluorescence imaging of invasive head and neck carcinoma cells with integrin αvβ6-targeting RGD-peptides: an approach to a fluorescence-assisted intraoperative cytological assessment of bony resection margins.
Nieberler M, Reuning U, Kessler H, Reichart F, Weirich G, Wolff KD. Nieberler M, et al. Among authors: reichart f. Br J Oral Maxillofac Surg. 2018 Dec;56(10):972-978. doi: 10.1016/j.bjoms.2018.11.003. Epub 2018 Nov 28. Br J Oral Maxillofac Surg. 2018. PMID: 30502043
Exploring the Role of RGD-Recognizing Integrins in Cancer.
Nieberler M, Reuning U, Reichart F, Notni J, Wester HJ, Schwaiger M, Weinmüller M, Räder A, Steiger K, Kessler H. Nieberler M, et al. Among authors: reichart f. Cancers (Basel). 2017 Sep 4;9(9):116. doi: 10.3390/cancers9090116. Cancers (Basel). 2017. PMID: 28869579 Free PMC article. Review.
Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3.
Weinmüller M, Rechenmacher F, Kiran Marelli U, Reichart F, Kapp TG, Räder AFB, Di Leva FS, Marinelli L, Novellino E, Muñoz-Félix JM, Hodivala-Dilke K, Schumacher A, Fanous J, Gilon C, Hoffman A, Kessler H. Weinmüller M, et al. Among authors: reichart f. Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16405-16409. doi: 10.1002/anie.201709709. Epub 2017 Nov 23. Angew Chem Int Ed Engl. 2017. PMID: 29072809
From a Helix to a Small Cycle: Metadynamics-Inspired αvβ6 Integrin Selective Ligands.
Di Leva FS, Tomassi S, Di Maro S, Reichart F, Notni J, Dangi A, Marelli UK, Brancaccio D, Merlino F, Wester HJ, Novellino E, Kessler H, Marinelli L. Di Leva FS, et al. Among authors: reichart f. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14645-14649. doi: 10.1002/anie.201803250. Epub 2018 May 2. Angew Chem Int Ed Engl. 2018. PMID: 29660806
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.
Merlino F, Daniele S, La Pietra V, Di Maro S, Di Leva FS, Brancaccio D, Tomassi S, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Reichart F, Cavallini C, Costa B, Piccarducci R, Taliani S, Da Settimo F, Martini C, Kessler H, Novellino E, Marinelli L. Merlino F, et al. Among authors: reichart f. J Med Chem. 2018 Jun 14;61(11):4791-4809. doi: 10.1021/acs.jmedchem.8b00004. Epub 2018 Jun 4. J Med Chem. 2018. PMID: 29775303
Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin.
Han J, Räder AFB, Reichart F, Aikman B, Wenzel MN, Woods B, Weinmüller M, Ludwig BS, Stürup S, Groothuis GMM, Permentier HP, Bischoff R, Kessler H, Horvatovich P, Casini A. Han J, et al. Among authors: reichart f. Bioconjug Chem. 2018 Nov 21;29(11):3856-3865. doi: 10.1021/acs.bioconjchem.8b00682. Epub 2018 Nov 13. Bioconjug Chem. 2018. PMID: 30380298
Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide.
Reichart F, Maltsev OV, Kapp TG, Räder AFB, Weinmüller M, Marelli UK, Notni J, Wurzer A, Beck R, Wester HJ, Steiger K, Di Maro S, Di Leva FS, Marinelli L, Nieberler M, Reuning U, Schwaiger M, Kessler H. Reichart F, et al. J Med Chem. 2019 Feb 28;62(4):2024-2037. doi: 10.1021/acs.jmedchem.8b01588. Epub 2019 Feb 6. J Med Chem. 2019. PMID: 30657681
21 results