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Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review.
Vinarov Z, Abdallah M, Agundez JAG, Allegaert K, Basit AW, Braeckmans M, Ceulemans J, Corsetti M, Griffin BT, Grimm M, Keszthelyi D, Koziolek M, Madla CM, Matthys C, McCoubrey LE, Mitra A, Reppas C, Stappaerts J, Steenackers N, Trevaskis NL, Vanuytsel T, Vertzoni M, Weitschies W, Wilson C, Augustijns P. Vinarov Z, et al. Eur J Pharm Sci. 2021 Jul 1;162:105812. doi: 10.1016/j.ejps.2021.105812. Epub 2021 Mar 20. Eur J Pharm Sci. 2021. PMID: 33753215 Free article. Review.
Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems.
Boyd BJ, Bergström CAS, Vinarov Z, Kuentz M, Brouwers J, Augustijns P, Brandl M, Bernkop-Schnürch A, Shrestha N, Préat V, Müllertz A, Bauer-Brandl A, Jannin V. Boyd BJ, et al. Among authors: vinarov z. Eur J Pharm Sci. 2019 Sep 1;137:104967. doi: 10.1016/j.ejps.2019.104967. Epub 2019 Jun 25. Eur J Pharm Sci. 2019. PMID: 31252052 Free article. Review.
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network.
Vinarov Z, Abrahamsson B, Artursson P, Batchelor H, Berben P, Bernkop-Schnürch A, Butler J, Ceulemans J, Davies N, Dupont D, Flaten GE, Fotaki N, Griffin BT, Jannin V, Keemink J, Kesisoglou F, Koziolek M, Kuentz M, Mackie A, Meléndez-Martínez AJ, McAllister M, Müllertz A, O'Driscoll CM, Parrott N, Paszkowska J, Pavek P, Porter CJH, Reppas C, Stillhart C, Sugano K, Toader E, Valentová K, Vertzoni M, De Wildt SN, Wilson CG, Augustijns P. Vinarov Z, et al. Adv Drug Deliv Rev. 2021 Apr;171:289-331. doi: 10.1016/j.addr.2021.02.001. Epub 2021 Feb 18. Adv Drug Deliv Rev. 2021. PMID: 33610694 Free article. Review.
Assessment of food effects during clinical development.
Vinarov Z, Butler J, Kesisoglou F, Koziolek M, Augustijns P. Vinarov Z, et al. Int J Pharm. 2023 Mar 25;635:122758. doi: 10.1016/j.ijpharm.2023.122758. Epub 2023 Feb 18. Int J Pharm. 2023. PMID: 36801481 Review.
21 results