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ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to chemotherapy in lung cancer.
Moreno T, Monterde B, González-Silva L, Betancor-Fernández I, Revilla C, Agraz-Doblas A, Freire J, Isidro P, Quevedo L, Blanco R, Montes-Moreno S, Cereceda L, Astudillo A, Casar B, Crespo P, Morales Torres C, Scaffidi P, Gómez-Román J, Salido E, Varela I. Moreno T, et al. Among authors: blanco r. Oncogene. 2021 Apr;40(16):2923-2935. doi: 10.1038/s41388-021-01748-y. Epub 2021 Mar 19. Oncogene. 2021. PMID: 33742126 Free PMC article.
The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells.
Lafita-Navarro MC, Liaño-Pons J, Quintanilla A, Varela I, Blanco R, Ourique F, Bretones G, Aresti J, Molina E, Carroll P, Hurlin P, Romero OA, Sanchez-Céspedes M, Eisenman RN, Delgado MD, León J. Lafita-Navarro MC, et al. Among authors: blanco r. J Biol Chem. 2020 Feb 14;295(7):2001-2017. doi: 10.1074/jbc.RA119.010389. Epub 2020 Jan 9. J Biol Chem. 2020. PMID: 31919096 Free PMC article.
MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells.
Molina E, García-Gutiérrez L, Junco V, Perez-Olivares M, de Yébenes VG, Blanco R, Quevedo L, Acosta JC, Marín AV, Ulgiati D, Merino R, Delgado MD, Varela I, Regueiro JR, Moreno de Alborán I, Ramiro AR, León J. Molina E, et al. Among authors: blanco r. Oncogene. 2023 Nov;42(45):3358-3370. doi: 10.1038/s41388-023-02846-9. Epub 2023 Sep 29. Oncogene. 2023. PMID: 37773203
MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).
Gómez-Casares MT, García-Alegria E, López-Jorge CE, Ferrándiz N, Blanco R, Alvarez S, Vaqué JP, Bretones G, Caraballo JM, Sánchez-Bailón P, Delgado MD, Martín-Perez J, Cigudosa JC, León J. Gómez-Casares MT, et al. Among authors: blanco r. Oncogene. 2013 Apr 25;32(17):2239-46. doi: 10.1038/onc.2012.246. Epub 2012 Jun 18. Oncogene. 2013. PMID: 22710719
A novel mutation in ADAMTS13 of a child with Upshaw-Schulman Syndrome.
Pérez-Rodríguez A, Batlle-López A, Blanco R, Varela I, León J, Delgado MD, Lourés E, Rodríguez-Trillo A, García-Rivero A, Costa-Pinto J, Batlle J, López-Fernández MF. Pérez-Rodríguez A, et al. Among authors: blanco r. Thromb Haemost. 2014 Nov;112(5):1065-8. doi: 10.1160/TH14-02-0116. Epub 2014 Jul 24. Thromb Haemost. 2014. PMID: 25057114 No abstract available.
MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis.
Lafita-Navarro MC, Blanco R, Mata-Garrido J, Liaño-Pons J, Tapia O, García-Gutiérrez L, García-Alegría E, Berciano MT, Lafarga M, León J. Lafita-Navarro MC, et al. Among authors: blanco r. Oncotarget. 2016 Oct 25;7(43):69536-69548. doi: 10.18632/oncotarget.11766. Oncotarget. 2016. PMID: 27588501 Free PMC article.
JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia.
Aranda-Tavío H, Recio C, Martín-Acosta P, Guerra-Rodríguez M, Brito-Casillas Y, Blanco R, Junco V, León J, Montero JC, Gandullo-Sánchez L, McNaughton-Smith G, Zapata JM, Pandiella A, Amesty A, Estévez-Braun A, Fernández-Pérez L, Guerra B. Aranda-Tavío H, et al. Among authors: blanco r. Biomed Pharmacother. 2021 Dec;144:112330. doi: 10.1016/j.biopha.2021.112330. Epub 2021 Oct 19. Biomed Pharmacother. 2021. PMID: 34673425 Free article.
1,167 results