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TGF-β-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity.
J Biol Chem. 2021 Jan-Jun;296:100545. doi: 10.1016/j.jbc.2021.100545. Epub 2021 Mar 17.
J Biol Chem. 2021.
PMID: 33741342
Free PMC article.
A comparative analysis of Smad-responsive motifs identifies multiple regulatory inputs for TGF-β transcriptional activation.
Itoh Y, Koinuma D, Omata C, Ogami T, Motizuki M, Yaguchi SI, Itoh T, Miyake K, Tsutsumi S, Aburatani H, Saitoh M, Miyazono K, Miyazawa K.
Itoh Y, et al. Among authors: omata c.
J Biol Chem. 2019 Oct 18;294(42):15466-15479. doi: 10.1074/jbc.RA119.009877. Epub 2019 Sep 3.
J Biol Chem. 2019.
PMID: 31481467
Free PMC article.
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ZEB1 and oncogenic Ras constitute a regulatory switch for stimulus-dependent E-cadherin downregulation.
Otake S, Itoh Y, Omata C, Saitoh M, Miyazawa K.
Otake S, et al. Among authors: omata c.
Cancer Sci. 2021 Jan;112(1):205-216. doi: 10.1111/cas.14701. Epub 2020 Nov 9.
Cancer Sci. 2021.
PMID: 33068045
Free PMC article.
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Smad2Δexon3 and Smad3 have distinct properties in signal transmission leading to TGF-β-induced cell motility.
Yokoyama T, Kuga T, Itoh Y, Otake S, Omata C, Saitoh M, Miyazawa K.
Yokoyama T, et al. Among authors: omata c.
J Biol Chem. 2023 Feb;299(2):102820. doi: 10.1016/j.jbc.2022.102820. Epub 2022 Dec 20.
J Biol Chem. 2023.
PMID: 36549646
Free PMC article.
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Indole-derived compound SIS3 targets a subset of activated Smad complexes.
Itoh Y, Sawaguchi T, Fu H, Omata C, Saitoh M, Miyazawa K.
Itoh Y, et al. Among authors: omata c.
J Biochem. 2023 Mar 31;173(4):283-291. doi: 10.1093/jb/mvac104.
J Biochem. 2023.
PMID: 36539324
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In Situ DNA Damaging Foci Analysis on Metaphase Chromosomes.
Omata C, Kato TA.
Omata C, et al.
Methods Mol Biol. 2019;1984:87-93. doi: 10.1007/978-1-4939-9432-8_10.
Methods Mol Biol. 2019.
PMID: 31267423
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Hypersensitivity of BRCA2 deficient cells to rosemary extract explained by weak PARP inhibitory activity.
Su C, Gius JP, Van Steenberg J, Haskins AH, Heishima K, Omata C, Iwayama M, Murakami M, Mori T, Maruo K, Kato TA.
Su C, et al. Among authors: omata c.
Sci Rep. 2017 Dec 1;7(1):16704. doi: 10.1038/s41598-017-16795-3.
Sci Rep. 2017.
PMID: 29196727
Free PMC article.
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PARP Inhibition by Flavonoids Induced Selective Cell Killing to BRCA2-Deficient Cells.
Su C, Haskins AH, Omata C, Aizawa Y, Kato TA.
Su C, et al. Among authors: omata c.
Pharmaceuticals (Basel). 2017 Oct 12;10(4):80. doi: 10.3390/ph10040080.
Pharmaceuticals (Basel). 2017.
PMID: 29023372
Free PMC article.
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