Kruse T - Search Results

1

AM833 Is a Novel Agonist of Calcitonin Family G Protein-Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists.

Fletcher MM, Keov P, Truong TT, Mennen G, Hick CA, Zhao P, Furness SGB, Kruse T, Clausen TR, Wootten D, Sexton PM. Fletcher MM, et al. Among authors: kruse t. J Pharmacol Exp Ther. 2021 Jun;377(3):417-440. doi: 10.1124/jpet.121.000567. Epub 2021 Mar 16. J Pharmacol Exp Ther. 2021. PMID: 33727283

2

Development of Cagrilintide, a Long-Acting Amylin Analogue.

Kruse T, Hansen JL, Dahl K, Schäffer L, Sensfuss U, Poulsen C, Schlein M, Hansen AMK, Jeppesen CB, Dornonville de la Cour C, Clausen TR, Johansson E, Fulle S, Skyggebjerg RB, Raun K. Kruse T, et al. J Med Chem. 2021 Aug 12;64(15):11183-11194. doi: 10.1021/acs.jmedchem.1c00565. Epub 2021 Jul 21. J Med Chem. 2021. PMID: 34288673 Free article.

3

Structure-Activity Relationships and Characterization of Highly Selective, Long-Acting, Peptide-Based Cholecystokinin 1 Receptor Agonists.

Sensfuss U, Kruse T, Skyggebjerg RB, Uldam HK, Vestergaard B, Huus K, Vinther TN, Reinau ME, Schéele S, Clausen TR. Sensfuss U, et al. Among authors: kruse t. J Med Chem. 2019 Feb 14;62(3):1407-1419. doi: 10.1021/acs.jmedchem.8b01558. Epub 2019 Jan 24. J Med Chem. 2019. PMID: 30624060

4

Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls.

Simonsen L, Lau J, Kruse T, Guo T, McGuire J, Jeppesen JF, Niss K, Sauerberg P, Raun K, Dornonville de la Cour C. Simonsen L, et al. Among authors: kruse t. PLoS One. 2022 Mar 4;17(3):e0264974. doi: 10.1371/journal.pone.0264974. eCollection 2022. PLoS One. 2022. PMID: 35245328 Free PMC article.

5

Lack of pharmacokinetic interaction between tiagabine and erythromycin.

Thomsen MS, Groes L, Agersø H, Kruse T. Thomsen MS, et al. Among authors: kruse t. J Clin Pharmacol. 1998 Nov;38(11):1051-6. doi: 10.1177/009127009803801110. J Clin Pharmacol. 1998. PMID: 9824787 Clinical Trial.

6

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.

Lau J, Bloch P, Schäffer L, Pettersson I, Spetzler J, Kofoed J, Madsen K, Knudsen LB, McGuire J, Steensgaard DB, Strauss HM, Gram DX, Knudsen SM, Nielsen FS, Thygesen P, Reedtz-Runge S, Kruse T. Lau J, et al. Among authors: kruse t. J Med Chem. 2015 Sep 24;58(18):7370-80. doi: 10.1021/acs.jmedchem.5b00726. Epub 2015 Sep 11. J Med Chem. 2015. PMID: 26308095

7

Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis.

Hein JB, Hertz EPT, Garvanska DH, Kruse T, Nilsson J. Hein JB, et al. Among authors: kruse t. Nat Cell Biol. 2017 Dec;19(12):1433-1440. doi: 10.1038/ncb3634. Epub 2017 Oct 30. Nat Cell Biol. 2017. PMID: 29084198

8

In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth.

Jiang N, Hjorth-Jensen K, Hekmat O, Iglesias-Gato D, Kruse T, Wang C, Wei W, Ke B, Yan B, Niu Y, Olsen JV, Flores-Morales A. Jiang N, et al. Among authors: kruse t. Oncogene. 2015 May 21;34(21):2764-76. doi: 10.1038/onc.2014.206. Epub 2014 Jul 28. Oncogene. 2015. PMID: 25065596

9

Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells.

Elmelund E, Galsgaard KD, Johansen CD, Trammell SAJ, Bomholt AB, Winther-Sørensen M, Hunt JE, Sørensen CM, Kruse T, Lau JF, Grevengoed TJ, Holst JJ, Wewer Albrechtsen NJ. Elmelund E, et al. Among authors: kruse t. iScience. 2022 Oct 6;25(11):105296. doi: 10.1016/j.isci.2022.105296. eCollection 2022 Nov 18. iScience. 2022. PMID: 36325048 Free PMC article.

10

A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment.

Kruse T, Larsen MS, Sedgwick GG, Sigurdsson JO, Streicher W, Olsen JV, Nilsson J. Kruse T, et al. EMBO Rep. 2014 Mar;15(3):282-90. doi: 10.1002/embr.201338101. Epub 2014 Jan 29. EMBO Rep. 2014. PMID: 24477933 Free PMC article.

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