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Psoriatic skin inflammation is promoted by c-Jun/AP-1-dependent CCL2 and IL-23 expression in dendritic cells.
Novoszel P, Holcmann M, Stulnig G, De Sa Fernandes C, Zyulina V, Borek I, Linder M, Bogusch A, Drobits B, Bauer T, Tam-Amersdorfer C, Brunner PM, Stary G, Bakiri L, Wagner EF, Strobl H, Sibilia M. Novoszel P, et al. Among authors: holcmann m. EMBO Mol Med. 2021 Apr 9;13(4):e12409. doi: 10.15252/emmm.202012409. Epub 2021 Mar 16. EMBO Mol Med. 2021. PMID: 33724710 Free PMC article.
TNFalpha shedding and epidermal inflammation are controlled by Jun proteins.
Guinea-Viniegra J, Zenz R, Scheuch H, Hnisz D, Holcmann M, Bakiri L, Schonthaler HB, Sibilia M, Wagner EF. Guinea-Viniegra J, et al. Among authors: holcmann m. Genes Dev. 2009 Nov 15;23(22):2663-74. doi: 10.1101/gad.543109. Genes Dev. 2009. PMID: 19933155 Free PMC article.
High-affinity IgE receptors on dendritic cells exacerbate Th2-dependent inflammation.
Sallmann E, Reininger B, Brandt S, Duschek N, Hoflehner E, Garner-Spitzer E, Platzer B, Dehlink E, Hammer M, Holcmann M, Oettgen HC, Wiedermann U, Sibilia M, Fiebiger E, Rot A, Maurer D. Sallmann E, et al. Among authors: holcmann m. J Immunol. 2011 Jul 1;187(1):164-71. doi: 10.4049/jimmunol.1003392. Epub 2011 May 27. J Immunol. 2011. PMID: 21622859
Epidermal EGFR controls cutaneous host defense and prevents inflammation.
Lichtenberger BM, Gerber PA, Holcmann M, Buhren BA, Amberg N, Smolle V, Schrumpf H, Boelke E, Ansari P, Mackenzie C, Wollenberg A, Kislat A, Fischer JW, Röck K, Harder J, Schröder JM, Homey B, Sibilia M. Lichtenberger BM, et al. Among authors: holcmann m. Sci Transl Med. 2013 Aug 21;5(199):199ra111. doi: 10.1126/scitranslmed.3005886. Sci Transl Med. 2013. PMID: 23966300
27 results