Light PE - Search Results

1

Evidence for the existence and potential roles of intra-islet glucagon-like peptide-1.

Campbell SA, Johnson J, Light PE. Campbell SA, et al. Among authors: light pe. Islets. 2021 Mar 4;13(1-2):32-50. doi: 10.1080/19382014.2021.1889941. Epub 2021 Mar 16. Islets. 2021. PMID: 33724156 Free PMC article. Review.

2

Hearts lacking plasma membrane K_ATP channels display changes in basal aerobic metabolic substrate preference and AMPK activity.

Youssef N, Campbell S, Barr A, Gandhi M, Hunter B, Dolinsky V, Dyck JRB, Clanachan AS, Light PE. Youssef N, et al. Among authors: light pe. Am J Physiol Heart Circ Physiol. 2017 Sep 1;313(3):H469-H478. doi: 10.1152/ajpheart.00612.2016. Epub 2017 Jun 30. Am J Physiol Heart Circ Physiol. 2017. PMID: 28667052 Free article.

3

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis.

Ondrusova K, Fatehi M, Barr A, Czarnecka Z, Long W, Suzuki K, Campbell S, Philippaert K, Hubert M, Tredget E, Kwan P, Touret N, Wabitsch M, Lee KY, Light PE. Ondrusova K, et al. Among authors: light pe. Sci Rep. 2017 Nov 27;7(1):16332. doi: 10.1038/s41598-017-16689-4. Sci Rep. 2017. PMID: 29180820 Free PMC article.

4

The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity.

Al Batran R, Gopal K, Aburasayn H, Eshreif A, Almutairi M, Greenwell AA, Campbell SA, Saleme B, Court EA, Eaton F, Light PE, Sutendra G, Ussher JR. Al Batran R, et al. Among authors: light pe. JCI Insight. 2019 Jan 10;4(1):e124643. doi: 10.1172/jci.insight.124643. JCI Insight. 2019. PMID: 30626749 Free PMC article.

5

Costarting sitagliptin with metformin is associated with a lower likelihood of disease progression in newly treated people with type 2 diabetes: a cohort study.

Campbell SA, Light PE, Simpson SH. Campbell SA, et al. Among authors: light pe. Diabet Med. 2020 Oct;37(10):1715-1722. doi: 10.1111/dme.14154. Epub 2019 Nov 6. Diabet Med. 2020. PMID: 31618475

6

Human islets contain a subpopulation of glucagon-like peptide-1 secreting α cells that is increased in type 2 diabetes.

Campbell SA, Golec DP, Hubert M, Johnson J, Salamon N, Barr A, MacDonald PE, Philippaert K, Light PE. Campbell SA, et al. Among authors: light pe. Mol Metab. 2020 Sep;39:101014. doi: 10.1016/j.molmet.2020.101014. Epub 2020 May 12. Mol Metab. 2020. PMID: 32413586 Free PMC article.

7

Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel.

Long W, Fatehi M, Soni S, Panigrahi R, Philippaert K, Yu Y, Kelly R, Boonen B, Barr A, Golec D, Campbell SA, Ondrusova K, Hubert M, Baldwin T, Lemieux MJ, Light PE. Long W, et al. Among authors: light pe. J Physiol. 2020 Oct;598(19):4321-4338. doi: 10.1113/JP279961. Epub 2020 Aug 13. J Physiol. 2020. PMID: 32721035 Free PMC article.

8

TRPV1 channels as a newly identified target for vitamin D.

Long W, Johnson J, Kalyaanamoorthy S, Light P. Long W, et al. Channels (Austin). 2021 Dec;15(1):360-374. doi: 10.1080/19336950.2021.1905248. Channels (Austin). 2021. PMID: 33825665 Free PMC article.

9

Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state.

Dai XQ, Camunas-Soler J, Briant LJB, Dos Santos T, Spigelman AF, Walker EM, Arrojo E Drigo R, Bautista A, Jones RC, Avrahami D, Lyon J, Nie A, Smith N, Zhang Y, Johnson J, Manning Fox JE, Michelakis ED, Light PE, Kaestner KH, Kim SK, Rorsman P, Stein RW, Quake SR, MacDonald PE. Dai XQ, et al. Among authors: light pe. Cell Metab. 2022 Feb 1;34(2):256-268.e5. doi: 10.1016/j.cmet.2021.12.021. Cell Metab. 2022. PMID: 35108513 Free PMC article.

10

Glucagon-like peptide-1 inhibits pancreatic ATP-sensitive potassium channels via a protein kinase A- and ADP-dependent mechanism.

Light PE, Manning Fox JE, Riedel MJ, Wheeler MB. Light PE, et al. Mol Endocrinol. 2002 Sep;16(9):2135-44. doi: 10.1210/me.2002-0084. Mol Endocrinol. 2002. PMID: 12198249

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