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Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.
Queval CJ, Fearns A, Botella L, Smyth A, Schnettger L, Mitermite M, Wooff E, Villarreal-Ramos B, Garcia-Jimenez W, Heunis T, Trost M, Werling D, Salguero FJ, Gordon SV, Gutierrez MG. Queval CJ, et al. Among authors: gutierrez mg. PLoS Pathog. 2021 Mar 15;17(3):e1009410. doi: 10.1371/journal.ppat.1009410. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33720986 Free PMC article.
The innate immune response in human tuberculosis.
Lerner TR, Borel S, Gutierrez MG. Lerner TR, et al. Among authors: gutierrez mg. Cell Microbiol. 2015 Sep;17(9):1277-85. doi: 10.1111/cmi.12480. Epub 2015 Jul 28. Cell Microbiol. 2015. PMID: 26135005 Free PMC article. Review.
Rab GTPases in Immunity and Inflammation.
Prashar A, Schnettger L, Bernard EM, Gutierrez MG. Prashar A, et al. Among authors: gutierrez mg. Front Cell Infect Microbiol. 2017 Sep 29;7:435. doi: 10.3389/fcimb.2017.00435. eCollection 2017. Front Cell Infect Microbiol. 2017. PMID: 29034219 Free PMC article. Review.
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.
Härtlova A, Herbst S, Peltier J, Rodgers A, Bilkei-Gorzo O, Fearns A, Dill BD, Lee H, Flynn R, Cowley SA, Davies P, Lewis PA, Ganley IG, Martinez J, Alessi DR, Reith AD, Trost M, Gutierrez MG. Härtlova A, et al. Among authors: gutierrez mg. EMBO J. 2018 Jun 15;37(12):e98694. doi: 10.15252/embj.201798694. Epub 2018 May 22. EMBO J. 2018. PMID: 29789389 Free PMC article.
Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo.
Vickers CF, Silva APG, Chakraborty A, Fernandez P, Kurepina N, Saville C, Naranjo Y, Pons M, Schnettger LS, Gutierrez MG, Park S, Kreiswith BN, Perlin DS, Thomas EJ, Cavet JS, Tabernero L. Vickers CF, et al. Among authors: gutierrez mg. J Med Chem. 2018 Sep 27;61(18):8337-8352. doi: 10.1021/acs.jmedchem.8b00832. Epub 2018 Sep 10. J Med Chem. 2018. PMID: 30153005 Free PMC article.
180 results