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Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation.
Queval CJ, Fearns A, Botella L, Smyth A, Schnettger L, Mitermite M, Wooff E, Villarreal-Ramos B, Garcia-Jimenez W, Heunis T, Trost M, Werling D, Salguero FJ, Gordon SV, Gutierrez MG. Queval CJ, et al. Among authors: gordon sv. PLoS Pathog. 2021 Mar 15;17(3):e1009410. doi: 10.1371/journal.ppat.1009410. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33720986 Free PMC article.
Characterization of the transcriptional regulator Rv3124 of Mycobacterium tuberculosis identifies it as a positive regulator of molybdopterin biosynthesis and defines the functional consequences of a non-synonymous SNP in the Mycobacterium bovis BCG orthologue.
Mendoza Lopez P, Golby P, Wooff E, Garcia JN, Garcia Pelayo MC, Conlon K, Gema Camacho A, Hewinson RG, Polaina J, Suárez García A, Gordon SV. Mendoza Lopez P, et al. Among authors: gordon sv. Microbiology (Reading). 2010 Jul;156(Pt 7):2112-2123. doi: 10.1099/mic.0.037200-0. Epub 2010 Apr 8. Microbiology (Reading). 2010. PMID: 20378651 Free PMC article.
Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection.
Magee DA, Conlon KM, Nalpas NC, Browne JA, Pirson C, Healy C, McLoughlin KE, Chen J, Vordermeier HM, Gormley E, MacHugh DE, Gordon SV. Magee DA, et al. Among authors: gordon sv. Tuberculosis (Edinb). 2014 Jul;94(4):441-50. doi: 10.1016/j.tube.2014.04.004. Epub 2014 May 5. Tuberculosis (Edinb). 2014. PMID: 24882682
A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.
Ní Cheallaigh C, Sheedy FJ, Harris J, Muñoz-Wolf N, Lee J, West K, McDermott EP, Smyth A, Gleeson LE, Coleman M, Martinez N, Hearnden CH, Tynan GA, Carroll EC, Jones SA, Corr SC, Bernard NJ, Hughes MM, Corcoran SE, O'Sullivan M, Fallon CM, Kornfeld H, Golenbock D, Gordon SV, O'Neill LA, Lavelle EC, Keane J. Ní Cheallaigh C, et al. Among authors: gordon sv. Immunity. 2016 Feb 16;44(2):368-79. doi: 10.1016/j.immuni.2016.01.019. Immunity. 2016. PMID: 26885859 Free PMC article.
Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle.
Villarreal-Ramos B, Berg S, Whelan A, Holbert S, Carreras F, Salguero FJ, Khatri BL, Malone K, Rue-Albrecht K, Shaughnessy R, Smyth A, Ameni G, Aseffa A, Sarradin P, Winter N, Vordermeier M, Gordon SV. Villarreal-Ramos B, et al. Among authors: gordon sv. Sci Rep. 2018 Jan 17;8(1):894. doi: 10.1038/s41598-017-18575-5. Sci Rep. 2018. PMID: 29343690 Free PMC article.
167 results