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Amyloid-β and islet amyloid pathologies link Alzheimer's disease and type 2 diabetes in a transgenic model.
Wijesekara N, Ahrens R, Sabale M, Wu L, Ha K, Verdile G, Fraser PE. Wijesekara N, et al. Among authors: sabale m. FASEB J. 2017 Dec;31(12):5409-5418. doi: 10.1096/fj.201700431R. Epub 2017 Aug 14. FASEB J. 2017. PMID: 28808140
These findings demonstrate that Abeta and IAPP are key factors in the overlapping pathologies of AD and T2D.-Wijesekara, N., Ahrens, R., Sabale, M., Wu, L., Ha, K., Verdile, G., Fraser, P. E. Amyloid-beta and islet amyloid pathologies link Alzheimer's disease and ty …
These findings demonstrate that Abeta and IAPP are key factors in the overlapping pathologies of AD and T2D.-Wijesekara, N., Ahrens, R., …
Efficient production of a mature and functional gamma secretase protease.
Khan I, Krishnaswamy S, Sabale M, Groth D, Wijaya L, Morici M, Berger I, Schaffitzel C, Fraser PE, Martins RN, Verdile G. Khan I, et al. Among authors: sabale m. Sci Rep. 2018 Aug 27;8(1):12834. doi: 10.1038/s41598-018-30788-w. Sci Rep. 2018. PMID: 30150752 Free PMC article.
Onset of hippocampal network aberration and memory deficits in P301S tau mice are associated with an early gene signature.
Przybyla M, van Eersel J, van Hummel A, van der Hoven J, Sabale M, Harasta A, Müller J, Gajwani M, Prikas E, Mueller T, Stevens CH, Power J, Housley GD, Karl T, Kassiou M, Ke YD, Ittner A, Ittner LM. Przybyla M, et al. Among authors: sabale m. Brain. 2020 Jun 1;143(6):1889-1904. doi: 10.1093/brain/awaa133. Brain. 2020. PMID: 32375177
Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Ke YD, van Hummel A, Au C, Chan G, Lee WS, van der Hoven J, Przybyla M, Deng Y, Sabale M, Morey N, Bertz J, Feiten A, Ippati S, Stevens CH, Yang S, Gladbach A, Haass NK, Kril JJ, Blair IP, Delerue F, Ittner LM. Ke YD, et al. Among authors: sabale m. Neuron. 2024 Apr 17;112(8):1249-1264.e8. doi: 10.1016/j.neuron.2024.01.022. Epub 2024 Feb 15. Neuron. 2024. PMID: 38366598
15 results