Ooi A - Search Results

1

Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia.

Goldfarb AN, Freeman KC, Sahu RK, Elagib KE, Holy M, Arneja A, Polanowska-Grabowska R, Gru AA, White Z 3rd, Khalil S, Kerins MJ, Ooi A, Leitinger N, Luckey CJ, Delehanty LL. Goldfarb AN, et al. Among authors: ooi a. Nat Commun. 2021 Mar 12;12(1):1645. doi: 10.1038/s41467-021-21938-2. Nat Commun. 2021. PMID: 33712594 Free PMC article.

2

Fumarate Mediates a Chronic Proliferative Signal in Fumarate Hydratase-Inactivated Cancer Cells by Increasing Transcription and Translation of Ferritin Genes.

Kerins MJ, Vashisht AA, Liang BX, Duckworth SJ, Praslicka BJ, Wohlschlegel JA, Ooi A. Kerins MJ, et al. Among authors: ooi a. Mol Cell Biol. 2017 May 16;37(11):e00079-17. doi: 10.1128/MCB.00079-17. Print 2017 Jun 1. Mol Cell Biol. 2017. PMID: 28289076 Free PMC article.

3

The Roles of NRF2 in Modulating Cellular Iron Homeostasis.

Kerins MJ, Ooi A. Kerins MJ, et al. Among authors: ooi a. Antioxid Redox Signal. 2018 Dec 10;29(17):1756-1773. doi: 10.1089/ars.2017.7176. Epub 2017 Sep 21. Antioxid Redox Signal. 2018. PMID: 28793787 Free PMC article. Review.

4

Fumarate hydratase inactivation in hereditary leiomyomatosis and renal cell cancer is synthetic lethal with ferroptosis induction.

Kerins MJ, Milligan J, Wohlschlegel JA, Ooi A. Kerins MJ, et al. Among authors: ooi a. Cancer Sci. 2018 Sep;109(9):2757-2766. doi: 10.1111/cas.13701. Epub 2018 Jul 20. Cancer Sci. 2018. PMID: 29917289 Free PMC article.

5

A catalogue of somatic NRF2 gain-of-function mutations in cancer.

Kerins MJ, Ooi A. Kerins MJ, et al. Among authors: ooi a. Sci Rep. 2018 Aug 27;8(1):12846. doi: 10.1038/s41598-018-31281-0. Sci Rep. 2018. PMID: 30150714 Free PMC article.

6

RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression.

Liu P, Rojo de la Vega M, Sammani S, Mascarenhas JB, Kerins M, Dodson M, Sun X, Wang T, Ooi A, Garcia JGN, Zhang DD. Liu P, et al. Among authors: ooi a. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10352-E10361. doi: 10.1073/pnas.1812125115. Epub 2018 Oct 11. Proc Natl Acad Sci U S A. 2018. PMID: 30309964 Free PMC article.

7

Genome-Wide CRISPR Screen Reveals Autophagy Disruption as the Convergence Mechanism That Regulates the NRF2 Transcription Factor.

Kerins MJ, Liu P, Tian W, Mannheim W, Zhang DD, Ooi A. Kerins MJ, et al. Among authors: ooi a. Mol Cell Biol. 2019 Jun 13;39(13):e00037-19. doi: 10.1128/MCB.00037-19. Print 2019 Jul 1. Mol Cell Biol. 2019. PMID: 31010806 Free PMC article.

8

Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells.

Liu P, Kerins MJ, Tian W, Neupane D, Zhang DD, Ooi A. Liu P, et al. Among authors: ooi a. J Biol Chem. 2019 Nov 29;294(48):18131-18149. doi: 10.1074/jbc.RA119.009591. Epub 2019 Oct 18. J Biol Chem. 2019. PMID: 31628195 Free PMC article.

9

CHML is an NRF2 target gene that regulates mTOR function.

Dodson M, Dai W, Anandhan A, Schmidlin CJ, Liu P, Wilson NC, Wei Y, Kitamura N, Galligan JJ, Ooi A, Chapman E, Zhang DD. Dodson M, et al. Among authors: ooi a. Mol Oncol. 2022 Apr;16(8):1714-1727. doi: 10.1002/1878-0261.13194. Epub 2022 Feb 28. Mol Oncol. 2022. PMID: 35184380 Free PMC article.

10

Aroylhydrazone Glycoconjugate Prochelators Exploit Glucose Transporter 1 (GLUT1) to Target Iron in Cancer Cells.

Sung YS, Kerimoglu B, Ooi A, Tomat E. Sung YS, et al. Among authors: ooi a. ACS Med Chem Lett. 2022 Aug 18;13(9):1452-1458. doi: 10.1021/acsmedchemlett.2c00250. eCollection 2022 Sep 8. ACS Med Chem Lett. 2022. PMID: 36105345 Free PMC article.

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