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Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion.
Stahnke S, Döring H, Kusch C, de Gorter DJJ, Dütting S, Guledani A, Pleines I, Schnoor M, Sixt M, Geffers R, Rohde M, Müsken M, Kage F, Steffen A, Faix J, Nieswandt B, Rottner K, Stradal TEB. Stahnke S, et al. Among authors: schnoor m. Curr Biol. 2021 May 24;31(10):2051-2064.e8. doi: 10.1016/j.cub.2021.02.043. Epub 2021 Mar 11. Curr Biol. 2021. PMID: 33711252 Free article.
Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis.
Citalán-Madrid AF, Vargas-Robles H, García-Ponce A, Shibayama M, Betanzos A, Nava P, Salinas-Lara C, Rottner K, Mennigen R, Schnoor M. Citalán-Madrid AF, et al. Among authors: schnoor m. Mucosal Immunol. 2017 Sep;10(5):1237-1247. doi: 10.1038/mi.2016.136. Epub 2017 Jan 25. Mucosal Immunol. 2017. PMID: 28120846 Free article.
Role of Src and Cortactin in Pemphigus Skin Blistering.
Kugelmann D, Rötzer V, Walter E, Egu DT, Fuchs MT, Vielmuth F, Vargas-Robles H, Schnoor M, Hertl M, Eming R, Rottner K, Schmidt A, Spindler V, Waschke J. Kugelmann D, et al. Among authors: schnoor m. Front Immunol. 2019 Apr 4;10:626. doi: 10.3389/fimmu.2019.00626. eCollection 2019. Front Immunol. 2019. PMID: 31024527 Free PMC article.
T cell functions and organ infiltration by leukemic T cells require cortactin.
Castellanos-Martínez R, León-Vega II, Guerrero-Fonseca IM, Vargas-Robles H, Jiménez-Camacho KE, Hernández-Galicia G, Ortiz-Navarrete VF, Rottner K, Medina-Contreras O, Schnoor M. Castellanos-Martínez R, et al. Among authors: schnoor m. J Leukoc Biol. 2023 Mar 1;113(3):315-325. doi: 10.1093/jleuko/qiad001. J Leukoc Biol. 2023. PMID: 36808495
114 results